Sublingual Glands
Sublingual Glands - Related Videos
09:29
Genetic Modification and Recombination of Salivary Gland Organ Cultures
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Cited by 20 •
2013
A technique to genetically manipulate epithelial cells within whole ex vivo cultured embryonic mouse submandibular glands (SMGs) using viral gene transfer is described. This method takes advantage of the innate ability of SMG epithelium and mesenchyme to spontaneously recombine after separation and infection of epithelial rudiments with adenoviral vectors.
05:18
Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct
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Cited by 17 •
2011
A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.
07:44
Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
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Cited by 5 •
2016
Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.
05:13
Gastric Fundic Glands Isolation: A Method to Isolate Fundic Glands from Human Stomach Tissue
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2023
This video describes a method to isolate gastric epithelial cells from the human fundic tissue. The isolated epithelial cells can be used as an in vitro model to study their regulatory roles in gastric physiology and pathophysiology.
04:06
Superior Lacrimal Gland Removal: A Surgical Technique to Remove the Palpebral and Orbital Parts of Superior Lacrimal Gland from Rabbit Model
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2025
This video describes the surgical procedure to remove the two parts: palpebral and orbital of the superior lacrimal gland from a rabbit to create a dry eye disease model. This rabbit model is suitable for studies of ocular surface homeostasis, pathophysiology and ocular therapeutics.
FAQs
Secretory cells release saliva through ducts by regulated exocytosis, a process in which cellular contents are expelled into a duct. This control links gland activity to the amount of fluid delivered, rather than requiring continuous, uncontrolled release. The duct pathway then conveys the secretion to the mouth, where it contributes to lubrication and oral protection.
Autonomic nerve signals adjust secretion according to oral stimuli, including food, taste, and chewing. These signals help coordinate gland activity with changing functional demands, such as preparing the mouth for swallowing or responding during eating. This regulation illustrates how the nervous system connects sensory information and mechanical activity with salivary gland physiology.
The predominantly mucus-rich secretion helps form a coating across oral surfaces. That coating supports lubrication and protection, making the secretion especially relevant to comfortable movement of materials through the mouth and maintenance of oral conditions. Comparing this secretion with those of other major salivary glands helps explain why different glands make distinct contributions to saliva.
Disrupted secretion can contribute to dry-mouth disorders and interfere with functions supported by saliva. Because salivary fluid helps with lubrication, swallowing, digestion, and oral protection, changes may affect nutrition, speech, dental health, and microbial balance. Inflammation is also an important context for studying how altered gland function influences oral biology.
They provide a focused example of glandular physiology, linking secretory cells, ducts, regulated exocytosis, and autonomic control. Their function also connects cellular mechanisms with whole-organism outcomes in the mouth. Studying these glands therefore supports research into oral biology, salivary secretion, dry-mouth disorders, inflammation, and the effects of altered saliva on health.
The mucus-rich secretion helps lubricate oral surfaces, supporting the movement of material during swallowing. If secretion is disrupted, reduced lubrication can be associated with effects on swallowing and speech, while broader changes in salivary function may influence nutrition. These links show how a localized gland contributes to several integrated oral functions.