Crystal Growth Dynamics

Crystal growth dynamics describes how crystals nucleate and increase in size and how their shape, structure, and properties change over time, making it important for controlling engineered materials. Growth begins when a solution, melt, or vapor becomes supersaturated or otherwise unstable, allowing stable nuclei to form; atoms, ions, or molecules then diffuse to the crystal surface and attach to available sites, with temperature, concentration, and transport conditions influencing the rate. Understanding these processes helps engineers optimize crystal size, purity, morphology, and defect levels in semiconductors, pharmaceuticals, ceramics, and other advanced materials. Models of growth dynamics also support scale-up and reproducible manufacturing.

Crystal Growth Dynamics - Related Videos

Education

JoVE Core - Analytical Chemistry

Crystal Growth: Principles of Crystallization

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2025

Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy. Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent – the...

Research

JoVE Journal - Bioengineering

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

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Cited by 9 •

2017

This study presents a methodology to prepare 3D, biodegradable, foam-like cell scaffolds based on biocompatible side-chain liquid crystal elastomers (LCEs). Confocal microscopy experiments show that foam-like LCEs allow for cell attachment, proliferation, and the spontaneous alignment of C2C12s myoblasts.

Orientational Transition in a Liquid Crystal Triggered by the Thermodynamic Growth of Interfacial Wetting Sheets

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2017

Here, we present a protocol to trigger an orientational transition of a liquid crystal in response to temperature. Methodologies are described for preparing a sample in order to observe the transition and the detailed transitional evolution.

Research

JoVE Journal - Neuroscience
Free Sample

In Situ Visualization of Axon Growth and Growth Cone Dynamics in Acute Ex Vivo Embryonic Brain Slice Cultures

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Cited by 4 •

2021

This protocol demonstrates a straightforward and robust method to study in situ axon growth and growth cone dynamics. It describes how to prepare ex vivo physiologically relevant acute brain slices and provides a user-friendly analysis pipeline.

Research

JoVE Journal - Biology
Free Sample

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

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Cited by 2 •

2021

Structural studies of biomacromolecules by crystallography require high-quality crystals. Here we demonstrate a protocol that can be used by OptiCrys (a fully automated instrument developed in our lab) and/or microdialysis buttons for growing large high-quality crystals based on knowledge of the crystallization phase diagram.

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