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Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
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Chapters
- 00:05Title
- 01:07Synthesis of α-Three-arm Star Block Copolymer (SBC-αCl)
- 04:37Fabrication of a Porous 3D Liquid Crystal Elastomer (LCE) Scaffold with Hexamethylene Diisocyanate (HDI) as a Crosslinker
- 07:27Seeding the LCE Scaffold Using Sterile Techniques and Imaging the LCE Construct
- 10:15Results: 3D Spatial Cell Cultures Prepared on LCE Foams
- 12:03Conclusion
This study presents a methodology to prepare 3D, biodegradable, foam-like cell scaffolds based on biocompatible side-chain liquid crystal elastomers (LCEs). Confocal microscopy experiments show that foam-like LCEs allow for cell attachment, proliferation, and the spontaneous alignment of C2C12s myoblasts.
