Barthel Index
Barthel Index - Related Videos
06:20
Syngeneic Mouse Orthotopic Allografts to Model Pancreatic Cancer
0 Views •
Cited by 5 •
2022
Syngeneic mouse orthotopic allografts of pancreatic ductal adenocarcinoma (PDAC) recapitulate the biology, phenotypes, and therapeutic responses of disease subtypes. Owing to their fast, reproducible tumor progression, they are widely used in preclinical studies. Here, we show common practices to generate these models, injecting syngeneic murine PDAC cultures into the pancreas.
06:29
Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
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Cited by 19 •
2021
Crystallographic fragment screening at the Helmholtz-Zentrum Berlin is performed using a workflow with dedicated compound libraries, crystal handling tools, fast data collection facilities and largely automated data analysis. The presented protocol intends to maximize the output of such experiments to provide promising starting points for downstream structure-based ligand design.
14:16
Analysis of Physiologic E-Selectin-Mediated Leukocyte Rolling on Microvascular Endothelium
0 Views •
Cited by 32 •
2009
This report provides a visual depiction of parallel-plate flow chamber analysis for studying leukocyte endothelial interactions under physiologic shear stress. This method is particularly useful for investigating the role of endothelial (E)-selectin and leukocyte E-selectin ligands that trigger leukocyte rolling on endothelial cell surfaces.
08:03
Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
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Cited by 8 •
2017
We present a model of ligament tissue in which three-dimensional constructs are treated with the human exercise-conditioned serum and analyzed for collagen content, function, and cellular biochemistry.
08:45
Tissue Engineering of the Intestine in a Murine Model
0 Views •
Cited by 29 •
2012
This article and the accompanying video present our protocol for generating tissue-engineered intestine in the mouse, using an organoid units-on-scaffold approach.
FAQs
The clinician assigns ratings according to the assistance a person requires for selected daily tasks. Greater independence is reflected in the scoring pattern, while greater need for help identifies functional limitations. Because the same task areas are considered across assessments, the resulting score supports a consistent description of day-to-day ability and care needs.
Interpretation depends on the profile across several domains rather than on a single activity. Feeding, bathing, dressing, and toileting describe personal self-care; bowel and bladder control address continence; transfers, mobility, and stair use reflect movement. Reviewing these areas together shows where assistance is concentrated within the overall functional picture.
Repeated ratings can show whether a person has become more independent, remained stable, or requires more assistance over time. This makes the index useful for tracking functional recovery after stroke, injury, or illness. Clinicians can compare assessments to describe change in practical daily abilities rather than relying only on the original clinical event.
It focuses on functional status and care needs, not on identifying the underlying disease. A person’s diagnosis may explain why assistance is needed, but the index records how that need appears in everyday activities such as transfers, toileting, or stair use. This distinction helps teams discuss practical independence alongside medical information.
A clinician reviews the specified activities of daily living and rates the person’s performance in each area, including self-care, continence, transfers, mobility, and stair use. The ratings produce an overall score that reflects assistance needs. Using the same task set helps clinicians communicate functional findings consistently across healthcare settings and over successive assessments.
It is especially relevant in rehabilitation and geriatric care, where functional independence and care requirements are central concerns. Clinicians may apply it after stroke, injury, or illness to characterize current ability and follow recovery. The results can also contribute to discharge planning by clarifying the level of help a person may need.
In care planning, the functional profile can help teams organize discussions about assistance needs before discharge. In research, standardized ratings provide a common way to evaluate functional outcomes and changes over time. This shared structure supports consistent communication across healthcare settings and clearer reporting of recovery after illness or injury.