Guidewire Technique

The guidewire technique is a minimally invasive method that uses a thin, flexible wire to establish and maintain access to a blood vessel, body lumen, or targeted anatomical site during medical procedures. Typically, clinicians introduce the guidewire through a needle or access device, advance it to the intended location, and then pass a catheter or other instrument over the wire while confirming position through imaging or procedural landmarks. This approach supports vascular access, catheter placement, drainage, and endovascular interventions, while helping clinicians control instrument trajectory and reduce repeated tissue puncture. Proper technique, sterility, and awareness of complications such as bleeding, perforation, or malposition are essential for safe application.

Guidewire Technique - Related Videos

Research

JoVE Journal - Medicine

The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire

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Cited by 8 •

2014

The overall goal is to enable clinicians to insert a central venous catheter under real-time ultrasound guidance via the right supraclavicular fossa view of the lower part of the superior vena cava. This view is useful for different catheter insertion sites, thrombosis detection before insertion and ultrasound guided correction of misplaced catheters.

Seldinger Technique Based Pulmonary Artery Catheterization: A Procedure to Insert Pulmonary Artery Catheter Through the Jugular Vein in a Porcine Model

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2025

In this video, we have demonstrated a step-by-step procedure of pulmonary artery catheterization by inserting an intravascular catheter through jugular vein and reach the pulmonary artery to measure the cardiac chamber pressure in porcine model.

Patient-derived Tumor Xenografting: A Technique to Generate Experimental Mouse Model for Evaluating Urothelial Cell Carcinoma

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2023

This video describes the procedure to generate an experimental xenograft murine model, which can be used for studying urothelial cell carcinoma progression.

Education

JoVE Lab Manual - Chemistry

Lab Techniques - Concepts

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2020

Measurement Accuracy The ability to repeat an experiment and get the same results, or reproducibility, is essential in scientific research. However, it’s impossible to repeat an experiment if you don’t know how you did it. Thus, scientists keep detailed records of their experiments in lab notebooks. These records include important information like the amount of each material used and descriptions of each step of the procedure. Equipment, like balances and volumetric or graduated glassware, is...

Assessing Vessel Perfusion via Angiography: A Technique to Introduce Contrast Agent in Descending Aorta to Visualize Blood Vessel Perfusion in Rabbit Model

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2025

This video describes the technique for performing angiography by injecting a contrast agent into the descending aorta to visualize blood vessel perfusion in a rabbit model. This technique helps to understand the perfusion in blood vessels with blockages and after treatment during recovery.

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