Ileal Conduit
Ileal Conduit - Related Videos
03:58
Schwann Cell-Seeded Conduits for Axonal Regeneration After Spinal Cord Injury
0 Views •
2025
Source: Lee, Y., et.al. Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap. J. Vis. Exp. (2017)This video demonstrates the use of a piezoelectric polymer conduit seeded with Schwann cells to promote axon regeneration in a transected rat spinal cord. The conduit provides structural guidance, while its bioelectric properties stimulate neurite outgrowth. Schwann cells within the conduit secrete...
04:58
Mouse Ileal Loop Model: A Surgical Model to Study Intestinal Permeability in the Mouse
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2025
This video demonstrates the generation of an ileal loop model to study intestinal permeability in a mouse model. This method provides a live model to understand the epithelial barrier function and consequent immune response.
04:35
Murine Ileal Resection Model: Studying Ileectomy-Induced Bile Metabolism in Murine Model
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2023
This video describes the detailed protocol for intestinal resection in a murine model. This technique provides insights into ileectomy-induced bile malabsorption, overaccumulation, and toxicity in the mouse intestine.
08:05
Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap
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Cited by 10 •
2017
This article describes a technique to insert a hollow conduit between the spinal cord stumps after complete transection and fill with Schwann cells (SCs) and injectable basement membrane matrix in order to bridge and promote axon regeneration across the gap.
10:15
The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits
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Cited by 17 •
2014
Blood exposure to polymeric blood conduits initiates the foreign body reaction that has been implicated in clinical complications. Here, the Chandler Loop Apparatus, an experimental tool mimicking blood perfusion through these conduits, is described. Appendage of recombinant CD47 results in decreased evidence of the foreign body reaction on these conduits.
FAQs
The reconstructed pathway does not recreate a bladder reservoir or a normal outlet controlled by the patient. Urine therefore moves from the ureters through the intestinal segment and exits at the abdominal stoma as it is produced. This noncontinent design makes an external collection pouch necessary for ongoing drainage.
Each component performs a separate function. The isolated ileal segment serves as the conduit, the ureters deliver urine from the upper urinary tract into that segment, and the stoma provides the external exit through the abdominal wall. Together, these structures replace the bladder’s pathway without restoring native urinary storage.
An ileal conduit prioritizes dependable drainage rather than continence or voluntary emptying. Because urine leaves continuously through the stoma, management centers on pouch collection and protection of the surrounding skin. This differs from reconstructions designed to hold urine temporarily, although the appropriate choice depends on bladder function and the clinical situation.
The procedure requires isolating a short portion of the small intestine, connecting the ureters to that segment, and bringing the segment to the abdominal surface as a stoma. The resulting pathway directs urine away from the bladder region and into an external pouch, establishing noncontinent drainage.
The approach is commonly considered after radical cystectomy for bladder cancer, when removal of the bladder eliminates normal urine storage and outflow. It may also be selected for severe bladder dysfunction when the native bladder cannot function normally. In these settings, the conduit offers a reliable reconstructive option.
Long-term management includes maintaining the external collection pouch and caring for the abdominal stoma and nearby skin. Since drainage is continuous rather than voluntarily controlled, pouch management and skin protection remain central to daily care. These requirements reflect the conduit’s noncontinent design and its role as a permanent urine exit pathway.