Behavioral Testing

Behavioral testing is the systematic measurement of an organism’s actions and responses to investigate how the brain supports behavior, making it a central approach in neuroscience. Researchers place animals or human participants in standardized tasks and quantify outcomes such as movement, learning, memory, anxiety-like responses, sensory processing, or social interaction under controlled conditions. Comparing performance across experimental groups, developmental stages, or neural manipulations helps link behavioral changes to brain circuits and biological mechanisms. These tests support studies of nervous system function, disease models, drug effects, and the development of interventions, while careful experimental design improves reproducibility and interpretation.

Behavioral Testing - Related Videos

Research

JoVE Journal - Biology

Olfactory Behavioral Testing in the Adult Mouse

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Cited by 68 •

2009

Fundamental, yet unique properties of the rodent olfactory system have led to its increasing study among biologists. A relatively simple assessment of its function is then also needed. Here we describe sensitive tests for the characterization of mouse olfactory sensitivity and preference.

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

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Cited by 402 •

2013

Disease, head injury, genetic modifications, and treatment of mice with drugs can have profound effects on behavior. Utilizing well-characterized and validated approaches such as marble burying and nestlet shredding, compulsive-like behaviors can be documented accurately in mice as models of human obsessive-compulsive disorder and autism spectrum disorder.

A Simple Behavioral Assay for Testing Visual Function in Xenopus laevis

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Cited by 26 •

2014

Xenopus laevis tadpoles prefer swimming on the white side of a black/white tank. This behavior is guided by their vision. Based on this behavior, we present a simple assay to test the visual function of tadpoles.

Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice

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Cited by 30 •

2018

Behavioral testing is used in pre-clinical trials to assess the phenotypic effects of a disease or treatment on an animal's wellbeing. In order to globally assess motor functioning, we selected tests for general locomotion, muscular strength, and coordination: the open field test, the mesh test, and the rotarod test, respectively.

Research

JoVE Journal - Behavior
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Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

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Cited by 4 •

2015

Prolonged and comprehensive monitoring of mice in a home-cage environment provides a deeper understanding of aberrant behavior in murine models of brain diseases. This paper describes the Integrated Behavioral Station (INBEST) as the key component of contemporary behavioral analysis.

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