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Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice
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JoVE Journal Behavior
Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice

Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice

DOI:
10.3791/55491-v

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06:54 min

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January 23, 2018

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, , , ,
1Centre for Neuroscience Studies,Queen’s University, 2Department of Biomedical and Molecular Sciences,Queen’s University, 3Medical Genetics/ Department of Pediatrics, Kingston General Hospital, Centre for Neuroscience Studies, and Department of Biomedical and Molecular Sciences,Queen’s University

Chapters

  • 00:05Title
  • 00:49Open Field Test
  • 02:54Mesh & Rotarod Test
  • 04:45Results: Treated Animals Outperform Untreated Animals
  • 05:31Conclusion

Summary

Automatic Translation

Automatic Translation

Behavioral testing is used in pre-clinical trials to assess the phenotypic effects of a disease or treatment on an animal's wellbeing. In order to globally assess motor functioning, we selected tests for general locomotion, muscular strength, and coordination: the open field test, the mesh test, and the rotarod test, respectively.

Tags

Keywords: Behavioral TestingLocomotionMuscular StrengthCoordinationMiceOpen Field TestMesh TestRotarod TestPreclinical TrialsMovementMotilitySmartWare SoftwareDigital Analog ConverterCalibrationData AnalysisAccelerated Protocol

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