Vitreous Chamber

The vitreous chamber is the large space between the eye’s lens and retina, filled with transparent, gel-like vitreous humor that supports vision and helps maintain the eye’s shape. This hydrated matrix transmits light toward retinal photoreceptors while its collagen and hyaluronan network provides structural support and distributes mechanical forces within the posterior eye. In neuroscience, the vitreous chamber is relevant to studying visual signal processing because changes in its clarity, composition, or organization can alter light transmission before neural detection begins. Its anatomy and age-related or disease-associated changes also inform research on retinal injury, ocular inflammation, and disorders that impair vision.

Vitreous Chamber - Related Videos

Research

JoVE Journal - Biology
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Evisceration of Mouse Vitreous and Retina for Proteomic Analyses

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Cited by 39 •

2011

The dissection technique illustrates evisceration of the vitreous, retina, and lens from the mouse eye, separation by centrifugation, and characterization with protein assays.

Research

JoVE Journal - Medicine

Whole Vitreous Humor Dissection for Vitreodynamic Analysis

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2015

The goal of this protocol is to show an effective technique to isolate whole, intact vitreous core and cortex from post mortem enucleated porcine eyes.

Research

JoVE Journal - Medicine
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Dissection of Human Vitreous Body Elements for Proteomic Analysis

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Cited by 28 •

2011

This video shows an effective technique for differentiating and dissecting the various semi-transparent structures of the human vitreous body in post mortem eyes.

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

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2026

The Foldable Capsular Vitreous Body (FCVB) is an intraocular implant that encapsulates silicone oil within a flexible capsule to reduce silicone oil-related complications. This protocol describes the surgical implantation of the FCVB via scleral incision for the treatment of complex retinal detachment and ocular trauma.

Preparing Porcine Eyes for Confocal Reflectance Microscopy to Visualize the Vitreous Collagen Fiber Network

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2025

This method visualizes the native structure of collagen fibers in the vitreous body using confocal reflectance microscopy.

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