Laser Activated Adhesive
Laser Activated Adhesive - Related Videos
06:32
A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration
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Cited by 32 •
2012
The fabrication of a novel, flexible thin film surgical adhesive from FDA approved ingredients, chitosan and indocyanine green is described. Bonding of this adhesive to collagenous tissue through a simple activation process with a low-powered infra-red laser is demonstrated.
09:14
Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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Cited by 21 •
2014
Static adhesion assay is a powerful tool that can be used to model the interactions between T lymphocytes and other cell types. Interactions are generated by injecting labeled T cells into wells coated with adhesion molecules, while a plate reader is used to quantify the number of adherent cells following serial washes.
09:31
Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution
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Cited by 1 •
2013
We measured the tension release in an axon that was partially lesioned with a laser dissector by simultaneous force spectroscopy measurement performed on an optically-trapped probe adhered to the membrane of the axon. The developed experimental protocol evaluates the axon adhesion to the culture substrate.
01:14
Adhesion
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2019
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules. Capillary action is a result of water’s adhesive tendencies. When a narrow glass...
07:40
Assay of Adhesion Under Shear Stress for the Study of T Lymphocyte-Adhesion Molecule Interactions
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Cited by 3 •
2016
This flow adhesion assay provides a simple, high impact model of T cell-epithelial cell interactions. A syringe pump is used to generate shear stress, and confocal microscopy captures images for quantification. The goal of these studies is to effectively quantify T cell adhesion using flow conditions.
FAQs
The light-absorbing component couples the adhesive to a selected laser wavelength. After absorbing energy, it can convert that input into localized heat or photochemical energy, which initiates curing, softens the material, or promotes bonding at the interface. Its function helps concentrate activation where joining is required instead of distributing energy broadly across nearby tissue or device components.
Laser wavelength determines how effectively the absorbing component responds, while focusing controls where the delivered energy is concentrated. Together, these variables provide temporal and spatial control over activation. A researcher can therefore target a specific bonding region and limit unnecessary exposure outside it, an important consideration when biological tissue or heat-sensitive engineered materials surround the interface.
Localized activation can trigger bonding without requiring the entire surrounding area to receive the same treatment. Depending on the adhesive system, heat may support curing or softening, whereas photochemical energy may initiate interfacial bonding. This distinction matters in bioengineering because controlled energy delivery can help preserve placement accuracy and reduce unintended effects on adjacent tissue or materials.
The main distinction is selective activation. Mechanical clamps provide physical holding force, while broadly applied chemical treatments expose a wider region to bonding agents. Laser activation instead uses focused energy to initiate or strengthen adhesion at chosen locations and times. This approach can reduce reliance on clamps or widespread chemical application, supporting more precise joining of biological and engineered surfaces.
A typical workflow places the adhesive between or on the surfaces to be joined, positions those surfaces accurately, and directs focused laser energy to the intended bonding region. The energy activates curing, softening, or interfacial bonding, after which the joined structure can be evaluated for placement and attachment. The exact sequence depends on the tissue or device application.
Researchers may select laser activated adhesive when a project requires controlled joining of tissue, biomaterials, or device components and when broad treatment or bulky mechanical support is undesirable. Potential uses described for bioengineering include wound closure, tissue repair, implant fixation, and biomedical-device fabrication. The method is especially relevant when precise placement or minimally invasive operation is a priority.