Infrared Laser Activation

Infrared laser activation is the use of focused infrared light to trigger a physical, chemical, or biological response, offering noncontact and spatially precise control in bioengineering. When infrared photons are absorbed by a target material or molecular chromophore, their energy can produce localized heating, alter molecular states, or initiate a designed reaction; wavelength, power, exposure time, and tissue or material properties determine the outcome. This approach supports remote activation of engineered systems, including responsive biomaterials, microscale devices, and therapeutic or diagnostic platforms, while limiting stimulation to selected regions. Understanding light absorption and energy transfer is therefore essential for improving precision, safety, and reproducibility.

Infrared Laser Activation - Related Videos

Research

JoVE Journal - Engineering

Characterizing Far-infrared Laser Emissions and the Measurement of Their Frequencies

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Cited by 4 •

2015

We describe the generation of far-infrared radiation using an optically pumped molecular laser along with the measurement of their frequencies with heterodyne techniques. The experimental system and techniques are demonstrated using difluoromethane (CH2F2) as the laser medium whose results include three new laser emissions and eight measured laser frequencies.

Functional Near-Infrared Spectroscopy for Recording Brain Activity During Social Interactions

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2025

Source: Reindl, V., et al. Conducting Hyperscanning Experiments with Functional Near-Infrared Spectroscopy. J. Vis. Exp. (2019) This video demonstrates the use of functional near-infrared spectroscopy (fNIRS) to measure brain activity during social interactions. Participants engage in a coordinated task that increases activity in the prefrontal cortex, a region critical for social behavior, while the system detects changes in light absorption due to blood oxygenation. By analyzing the synchrony...

Control of Cell Geometry through Infrared Laser Assisted Micropatterning

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2021

The protocol presented here enables automated fabrication of micropatterns that standardizes cell shape to study cytoskeletal structures within mammalian cells. This user-friendly technique can be set up with commercially available imaging systems and does not require specialized equipment inaccessible to standard cell biology laboratories.

A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration

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Cited by 32 •

2012

The fabrication of a novel, flexible thin film surgical adhesive from FDA approved ingredients, chitosan and indocyanine green is described. Bonding of this adhesive to collagenous tissue through a simple activation process with a low-powered infra-red laser is demonstrated.

Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)

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Cited by 19 •

2016

A mass spectrometry imaging (MSI) source operated at atmospheric pressure was developed by coupling mid-infrared laser desorption and electrospray post-ionization. Exogenous ice matrix was used as the energy-absorbing matrix to facilitate resonant desorption of tissue-related material. This manuscript provides a step-by-step protocol for performing IR-MALDESI MSI of whole-body neonatal mouse.

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