Fluoridated Toothpaste
Fluoridated Toothpaste - Related Videos
09:57
18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
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Cited by 3 •
2020
The synthesis of fluorine-18 (18F) labeled radiopharmaceuticals for positron emission tomography typically requires months of experience. When incorporated into a radiotracer, the silicon-fluoride acceptor (SiFA) motif enables a simple 18F-labeling protocol that is independent of costly equipment and preparatory training, while reducing precursor quantity needed and utilizing milder reaction conditions.
14:20
High Throughput SiRNA Screening for Chloropicrin and Hydrogen Fluoride-Induced Cornea Epithelial Cell Injury
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Cited by 9 •
2018
High throughput small inhibitory RNA screening is an important tool that could help to more rapidly elucidate the molecular mechanisms of chemical cornea epithelial injury. Herein, we present the development and validation of exposure models and methods for the high throughput screening of hydrogen fluoride- and chloropicrin-induced cornea epithelial injury.
06:57
Quantification of Fluoride in Serum, Bone, and Teeth in a Murine Model Using Hexamethyldisiloxane-Facilitated Diffusion and Ion-Selective Electrode Measurements
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2026
This protocol describes the preparation of hexamethyldisiloxane (HMDS)-facilitated diffusion dishes, followed by ion-selective electrode measurements to quantify fluoride ion mass in the serum, bone, and teeth of mice. The method provides a sensitive, calibration-based approach for evaluating fluoride accumulation in biological specimens.
07:43
Calibration Curves
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2023
Source: Laboratory of Dr. B. Jill Venton - University of Virginia Calibration curves are used to understand the instrumental response to an analyte and predict the concentration in an unknown sample. Generally, a set of standard samples are made at various concentrations with a range than includes the unknown of interest and the instrumental response at each concentration is recorded. For more accuracy and to understand the error, the response at each concentration can be repeated so an error...
08:22
Simultaneous fMRI and Electrophysiology in the Rodent Brain
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Cited by 43 •
2010
We have developed a method for simultaneous functional magnetic resonance imaging and electrophysiological recording in the rodent brain, providing a platform for the investigation of the relationship between neural activity and the blood oxygenation level dependent (BOLD) MRI signal.
FAQs
Fluoride ions available in saliva and dental plaque during brushing can reduce acid-driven demineralization, the loss of mineral from enamel. This shifts conditions toward preserving tooth structure when acids challenge the surface. The effect is topical, allowing fluoride to act where exposure occurs during routine oral care.
Early enamel lesions can regain mineral when fluoride supports remineralization. The repaired mineral is also more resistant to later acid attack, so the benefit extends beyond immediate repair. This helps explain how regular brushing can support enamel preservation before a cavity becomes established.
Fluoride may also reduce bacterial acid production in dental plaque. That matters because bacterial acids contribute to the conditions that drive enamel demineralization. Consequently, toothpaste can influence both the tooth surface and a plaque-related contributor to acid stress, complementing its mineral-preserving actions during routine brushing.
Consistency matters because tooth surfaces repeatedly encounter acid challenges, particularly when sugar exposure occurs frequently. Regular brushing provides recurring opportunities for fluoride to act in saliva, plaque, and enamel. It should therefore be combined with habits that reduce frequent sugar exposure, rather than treated as an isolated cavity-prevention measure.
During routine use, fluoridated toothpaste is applied with a toothbrush, making brushing the delivery step for topical fluoride. Its preventive role should be considered alongside continuing oral care, routine dental care, and dietary habits that limit frequent sugar exposure. Together, these measures form a practical strategy for limiting cavity formation.
Its medical importance lies in prevention at both individual and population levels. Children and adults can use this practical, low-cost topical approach to help limit cavity formation. Widespread regular brushing, combined with dental care and reduced frequent sugar exposure, supports population oral health rather than addressing only established disease.