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Onderzoeken eiwit-eiwit interacties in levende cellen met behulp van bioluminescentie resonantie energieoverbrenging

Article DOI: 10.3791/51438-v • 11:46 min • May 26th, 2014
May 26th, 2014 •
*1, *1, 1, 1,2
1Language and Genetics Department, Max Planck Institute for Psycholinguistics, 2Donders Institute for Brain, Cognition and Behaviour
* These authors contributed equally

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Interacties tussen eiwitten zijn fundamenteel voor alle cellulaire processen. Met Bioluminescentie Resonance Energy Transfer, kan de interactie tussen twee eiwitten worden gecontroleerd in levende cellen en in real time. Bovendien kunnen de effecten van potentieel pathogene mutaties worden beoordeeld.

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Cellular Biology eiwit-eiwit interacties Bioluminescence Resonance Energy Transfer Levende cellen transfectie Luciferase geel fluorescent eiwit mutaties
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