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JoVE Journal Cancer Research
Potensering af Anticancer antistof effektivitet af antineoplastiske stoffer
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Potensering af Anticancer antistof effektivitet af antineoplastiske stoffer: påvisning af antistof-drug synergi med kombination indeks ligning

Article DOI: 10.3791/58291-v • 15:04 min • January 19th, 2019
January 19th, 2019 •
*1, *1, *1,2, *1, *1,3, *1,3
1Centre de Recherche en Cancérologie et Immunologie Nantes Angers (CRCINA), Institut national de la santé et de la recherche médicale (INSERM), Université d'Angers, Université de Nantes, Nantes, France, 2Service de chirurgie pédiatrique, Centre hospitalier universitaire (CHU) de Nantes, Nantes, France, 3Unité de Formation et Recherche (UFR) des Sciences Pharmaceutiques et Biologiques, Université de Nantes, Nantes, France
* These authors contributed equally

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Denne protokol beskriver hvordan man vurdere synergi mellem en anticancer antistof og antineoplastiske stoffer i prækliniske modeller ved hjælp af kombination indeks ligning af Chou og Talalay.

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Kræftforskning spørgsmålet 143 kræftforskning stof udvikling antistof-drug kombination antistof-drug interaktion MTT assay antistof-drug synergi kombination indeks ligning in vitro celle line model tumor xenograft model
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