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JoVE Journal Cancer Research
En tredimensionell sfäroidmodell för att undersöka tumör-stromal interaktion i hepatocellulärt karcinom
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En tredimensionell sfäroidmodell för att undersöka tumör-stromal interaktion i hepatocellulärt karcinom

Article DOI: 10.3791/62868-v • 12:24 min • September 30th, 2021
September 30th, 2021 •
*1,2, *2, 2, 2, *3, *4,5
1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust
* These authors contributed equally

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Omfattande in vitro-modeller som troget rekapitulerar den relevanta mänskliga sjukdomen saknas. Den aktuella studien presenterar tredimensionella (3D) tumör sfäroid skapande och kultur, ett tillförlitligt in vitro verktyg för att studera tumör-stromal interaktion i mänskliga hepatocellular carcinom.

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Cancerforskning nummer 175
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