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使用数字液滴聚合酶链反应测量单细胞线粒体DNA拷贝数和异质性

Article DOI: 10.3791/63870-v • 09:15 min • July 12th, 2022
July 12th, 2022 •
1,2, 1,2
1Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, 2Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus

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在这里，我们提出了一种用于测量单细胞中绝对线粒体（mt）DNA拷贝数和mtDNA缺失异质水平的方案。

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医学，第185期，
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