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Ikke-invasiv PET/MR-billeddannelse i en ortopisk musemodel af hepatocellulært karcinom

Article DOI: 10.3791/63958-v • 07:47 min • August 31st, 2022
August 31st, 2022 •
*1,2, *3, 2, 1, 4, 1,5, 3
1Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 2Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, 3Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, 4Department of Biomedical Engineering, The Chinese University of Hong Kong, 5Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital
* These authors contributed equally

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Her præsenterer vi en protokol til oprettelse af ortotopiske hepatocellulære carcinomxenotransplantater med og uden leverarterieligering og udfører ikke-invasiv positronemissionstomografi (PET) billeddannelse af tumorhypoxi ved hjælp af [18 F] Fluoromisonidazol ([18 F] FMISO) og [18 F] fluorodeoxyglucose ([18F] FDG).

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Kræftforskning nr. 186
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