Photoresist Patterning

Photoresist patterning is a microfabrication technique that transfers precise geometric designs onto a substrate, enabling the production of integrated circuits, microelectromechanical systems, and other engineered devices. The process coats a surface with a light-sensitive polymer, selectively exposes it through a photomask, and develops the film so that illuminated or unilluminated regions dissolve, depending on whether the resist is positive or negative. The resulting resist pattern protects selected areas during etching, deposition, or implantation, allowing structures to be formed with controlled dimensions. Its resolution, alignment, and process consistency strongly influence device performance and support advances in semiconductor manufacturing, sensors, and microscale engineering.

Photoresist Patterning - Related Videos

Research

JoVE Journal - Bioengineering

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

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Cited by 9 •

2017

A microfluidic biosensor platform was designed and fabricated using low-cost dry film photoresist technology for the rapid and sensitive quantification of various analytes. This single-use system allows for the electrochemical readout of on-chip-immobilized enzyme-linked assays by means of the stop-flow technique.

Research

JoVE Journal - Bioengineering
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Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

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Cited by 9 •

2014

This protocol describes a microfabrication-compatible method for cell patterning on SiO2. A predefined parylene-C design is photolithographically printed on SiO2 wafers. Following incubation with serum (or other activation solution) cells adhere specifically to (and grow according to the conformity of) underlying parylene-C, whilst being repulsed by SiO2 regions.

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement

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Cited by 5 •

2011

Self-assembled monolayers (SAMs) formed from long chain alkane thiols on gold provide well-defined substrates for the formation of protein patterns and cell confinement. Microcontact printing of hexadecanethiol using a polydimethylsiloxane (PDMS) stamp followed by backfilling with a glycol-terminated alkane thiol monomer produces a pattern where protein and cells adsorb only to the stamped hexadecanethiol region.

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes

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Cited by 1 •

2007

Non-fouling PEG silane monolayer was desorbed from individually addressable ITO electrodes on glass by application of a reductive potential. Electrochemical stripping of PEG-silane layer from ITO microelectrodes allowed for cell adhesion to take place in a spatially defined fashion, with cellular patterns corresponding closely to electrode patterns.

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

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Cited by 8 •

2017

A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.

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