Artificial Skin

Artificial skin refers to engineered materials or living constructs designed to replace, repair, or replicate the functions of natural skin. In medicine, these systems combine biocompatible scaffolds, polymers, hydrogels, or cultured cells to support wound coverage, tissue regeneration, and restoration of the skin’s protective barrier. Some advanced designs also incorporate sensors that detect pressure, temperature, or chemical signals, translating these stimuli into electrical responses that can support sensory feedback. Applications include treating burns, chronic wounds, and extensive tissue loss, while ongoing research aims to improve integration with surrounding tissue, reduce scarring, and create more functional substitutes for transplantation and prosthetic technologies.

Artificial Skin - Related Videos

Education

JoVE Lab Manual - Biology

Artificial Selection - Concepts

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2019

Natural Selection and Adaptive Evolution In natural settings, adaptive evolution takes place by natural selection, a process in which differences in traits lead to differences in survival and reproductive success between individuals. This happens because individuals with certain phenotypes have a higher probability of survival and/or produce more surviving offspring than individuals with other phenotypes. A classic example of this was demonstrated by Rosemary and Peter Grant studying the...

Artificial Selection - Student Protocol

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2019

Observing Artificial Selection in Plants ExpandTo begin the experiment, collect five two-week old grown plants from the generation one population that appear healthy. Note: Plants should appear green, not wilted, and not have damaged leaves. Experimental Hypothesis: The experimental hypothesis for this lab might be that the number of lead trichomes varies naturally, but the average number will increase over generations if only plants with the highest number of trichomes are interbred or...

Research

JoVE Journal - Bioengineering

Design and Construction of Artificial Extracellular Matrix (aECM) Proteins from Escherichia coli for Skin Tissue Engineering

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Cited by 6 •

2015

Recombinant technologies have enabled material designers to create novel artificial proteins with customized functionalities for tissue engineering applications. For example, artificial extracellular matrix proteins can be designed to incorporate structural and biological domains derived from native ECMs. Here, we describe the construction and purification of aECM proteins containing elastin-like repeats.

Research

JoVE Journal - Medicine
Free Sample

Implantation of the Syncardia Total Artificial Heart

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Cited by 12 •

2014

The purpose of this manuscript is to briefly review indications, management, and outcomes for the total artificial heart. Video operative techniques for device implantation are presented.

Harvesting Sperm and Artificial Insemination of Mice

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Cited by 18 •

2007

This protocol demonstrates methods for extracting sperm from the testes of males and then inseminating female mice. This procedure is useful when precise time is needed in developmental studies as well as transgenic work.

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