Meniere's Disease

Meniere's disease is a chronic disorder of the inner ear that causes recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus, and a feeling of fullness or pressure in the affected ear. It is associated with endolymphatic hydrops, in which excess or poorly regulated inner-ear fluid alters pressure within the cochlea and vestibular organs, disrupting hearing and balance signals. Clinical evaluation combines symptom history, hearing tests, and vestibular assessment to distinguish Meniere's disease from other causes of dizziness and hearing loss. Management may include dietary and medication strategies, rehabilitation, injections, or surgery, helping reduce attacks and preserve function.

Meniere's Disease - Related Videos

Research

JoVE Journal - Medicine

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

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Cited by 1 •

2023

Endolymphatic duct blockage is a relatively new surgical method for patients suffering from Ménière's disease. Following a regular mastoidectomy, the endolymphatic duct is identified and ligated using a regular titanium hemoclip. The effectiveness of this procedure is currently being assessed in a randomized trial.

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears

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Cited by 4 •

2018

To evaluate morphological changes of cranial nerves such as loss of neural structures or swelling of cranial nerves in Menière's Disease (MD) or in healthy persons in vivo, a protocol of evaluation has been developed using magnetic resonance imaging (MRI). Additional MRI-based confirmation of MD was performed.

Education

JoVE Science Education - Advanced Biology

An Overview of Genetics and Disease

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2023

Many human diseases are associated with mutations or variations in genetic sequences. Some of these genetic variants are heritable, passed down from generation to generation, while others arise sporadically during an organism’s life and cause diseases such as cancer. Researchers are trying to identify and characterize these genetic alterations in the hopes of improving diagnosis and therapeutic options for patients.In this video, we will examine the history of genetic disease research, and...

Research

JoVE Journal - Immunology and Infection
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Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model

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Cited by 12 •

2012

The inoculation of Trypanosoma cruzi in fertile eggs prior to incubation renders the parasite kDNA minicircle integration in embryo cells genome. Crossbreeding reveals the vertical transfer of the mutations to progeny. The kDNA integrates into coding regions at several chromosomes and the chickens die with an inflammatory autoimmune heart disease.

Assessment of Vascular Function in Patients With Chronic Kidney Disease

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Cited by 25 •

2014

The degree of vascular dysfunction and contributing physiological mechanisms can be assessed in patients with chronic kidney disease by measuring brachial artery flow-mediated dilation, aortic pulse-wave velocity, and vascular endothelial cell protein expression.

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