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Biology

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Molecular Biology

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Gene Expression

DNA Methylation and Histone Changes

Description

Epigenetic regulation controls gene activity without changing the DNA sequence. It helps determine when genes are turned on or off in a cell.

Two major epigenetic mechanisms are DNA methylation and histone modification. DNA methylation adds chemical groups to DNA, while histone changes affect how...

Transcript

Epigenetic regulation refers to changes in gene expression that can be inherited without changes to the genetic sequence. This occurs during the normal course of development and can also be caused by environmental factors, such as diet, exposure to toxic substances, and stress.

Epigenetic regulation occurs through three main mechanisms: ...

Tags

DNA MethylationHistone ModificationRNA Based ProcessesX Chromosome InactivationCpG IslandsTumor Suppressor GenesCell Cycle RegulatorsTranscription FactorsChromatin Structure