Genomic Imprinting in Human Disease

Genomic imprinting affects how some inherited genes are turned on or off in human cells. Diploid organisms inherit chromosomes from both parents, and each gene usually has two alleles. In most cases, both alleles are expressed. If one allele is missing or mutated, the other can often compensate, but some genes do not work th...

Genomic imprinting is a phenomenon where the regulation of gene expression is influenced by which parent passed the gene to its offspring.

Somatic cells of many organisms, such as mammals, are diploid, that is they have two copies of the genome- one inherited from the father and one from the mother. Copies of the same gene in somatic cell...