This is a free preview. For full access
Neuroscience
Patch Clamp Electrophysiology
Description
Neuron cell membranes are populated with ion channels that control the movement of charge into and out of the cell, thereby regulating neuron firing. One extremely useful technique for investigating the biophysical properties of these channels is called patch clamp recording. In this method, neuroscientists place a polished ...
Show More
Transcript
Patch clamp recording is an extremely useful technique for investigating the biophysical properties of the ion channels that control neuronal activation.
The procedure involves pressing a glass micropipette against a cell in order to isolate a small “patch” of membrane that contains one or more ion channels.
Show More