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Neuroscience

Targeting Neural Genes in Mouse Embryos

Description

In utero electroporation is a method for delivering genetic material into mouse embryos while they are still developing in the uterus. It uses brief electrical pulses to open temporary pores in cell membranes. This lets researchers place material into cells in a targeted way and study neural development.

Transcript

In utero electroporation is a key technique for studying the molecular mechanisms that guide neurodevelopment. By injecting DNA to alter gene expression in specific regions of the developing rodent brain, researchers can study the proliferation, differentiation, migration, and maturation of neural cells in the contex...

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