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Advanced Biology

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Neuroscience

Culturing Embryonic Brain Tissue

Description

Embryonic brain tissue can be grown in culture to help scientists study how the nervous system develops. This approach lets researchers follow cell differentiation, cell migration, and changes in cell shape while the tissue stays in an organotypic state. Organotypic means the tissue is removed from the body, but its normal c...

Transcript

Explant cultures serve as a technique to investigate the development of specific cell populations and neural structures. In developmental neuroscience experiments, explants are neural tissues excised from an embryo for continued development in vitro. These cultures give researchers the ability to manipulate and visua...

Tags

Explant CultureNeural TissueSlice CultureEmbryonic Mouse BrainVibratome SectioningAgarose EmbeddingConfocal MicroscopyCell Migration AssaysCo culture AssaysAxon Guidance Assays

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