Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

Yongchun Jiang; Junxiao Yin; Biyi Zhao; Yajie Zhang; Tingting Peng; Wanqi Zhuang; Siqing Wang; Siqi Huang; Meilian Zhong; Yanni Zhang; Guibing Tang; Bingchi Shen; Haining Ou; Yuxin Zheng; Qiang Lin

doi:10.3791/65405

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Method Article

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

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DOI:

10.3791/65405

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September 1st, 2023

Yongchun Jiang^*¹^,²^,³ , Junxiao Yin^*⁴ , Biyi Zhao¹^,³^,⁵ , Yajie Zhang¹^,³ , Tingting Peng¹^,³ , Wanqi Zhuang¹^,³ , Siqing Wang¹^,³ , Siqi Huang¹^,³ , Meilian Zhong¹^,³ , Yanni Zhang¹^,³ , Guibing Tang¹^,³ , Bingchi Shen⁶ , Haining Ou¹^,³ , Yuxin Zheng^*²^,³ , Qiang Lin^*²^,³

¹Guangzhou Medical University, ²Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University, ³Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University, ⁴Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, ⁵School of Traditional Chinese Medicine, Jinan University, ⁶Department of Stomatology, Second Clinical Medical College, Dongguan Campus of Guangdong Medical University

^* These authors contributed equally

Erratum Notice

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Summary

The purpose of this study is to provide an important reference for the standard clinical operation of motor imagery brain-computer interface (MI-BCI) for upper limb motor dysfunction after stroke.

Abstract

The rehabilitation effect of patients with moderate or severe upper limb motor dysfunction after stroke is poor, which has been the focus of research owing to the difficulties encountered. Brain-computer interface (BCI) represents a hot frontier technology in brain neuroscience research. It refers to the direct conversion of the sensory perception, imagery, cognition, and thinking of users or subjects into actions, without reliance on peripheral nerves or muscles, to establish direct communication and control channels between the brain and external devices. Motor imagery brain-computer interface (MI-BCI) is the most common clinical application of rehabilitation as a non-invasive means of rehabilitation. Previous clinical studies have confirmed that MI-BCI positively improves motor dysfunction in patients after stroke. However, there is a lack of clinical operation demonstration. To that end, this study describes in detail the treatment of MI-BCI for patients with moderate and severe upper limb dysfunction after stroke and shows the intervention effect of MI-BCI through clinical function evaluation and brain function evaluation results, thereby providing ideas and references for clinical rehabilitation application and mechanism research.

Introduction

Nearly 85% of stroke patients have motor dysfunction¹, especially due to the limited rehabilitation effect of patients with moderate and severe upper limb motor dysfunction, which seriously affects patients' ability to live independent daily lives and has been the focus and difficulty of research. Non-invasive brain-computer interface (BCI) is known as an emerging treatment for rehabilitation of motor dysfunction after stroke². BCI is the direct conversion of the sensory perception, imagery, cognition, and thinking of users or subjects into actions, without reliance on peripheral nerves or muscles, to establish direct co....