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TOPICAL COLLECTIONS

Invasive Procedures for the Diagnosis and Staging of Patients Suspected of Lung Cancer
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Kristoffer Mazanti Cold

Kristoffer Mazanti Cold

University of Copenhagen and the Capital Region of Denmark, 2100 Copenhagen, Denmark, Rigshospitalet, Copenhagen Academy for Medical Education and Simulation (CAMES)

Dr. Kristoffer Mazanti Cold is a Ph.D.-alumni of Copenhagen Academy for Medical Education and Simulation (CAMES), Rigshospitalet, and the University of Copenhagen, Denmark. His research focuses on finding objective assessment measures of endoscopic disciplines and utilizing these to enhance medical education and performance. As novice bronchoscopist desire more feedback when learning the procedure, he has developed an automatic and objective assessment of scope handling: The Motor Bronchoscopy Skills Score and the Structured Progression Score, indicating a systematic inspection of the bronchial tree. The goal is to develop a fully automatic training, assessment, and feedback system in bronchoscopy and endobronchial ultrasound sampling (EBUS) based on artificial intelligence.

Paul Frost Clementsen

Paul Frost Clementsen

Copenhagen Academy for Medical Education and Simulation (CAMES)

Paul Frost Clementsen is a pulmonologist at Copenhagen Academy for Medical Education and Simulation (CAMES) in Denmark. He is particularly interested in diagnosing and staging lung cancer using real-time guided fine needle biopsy via the esophagus (EUS-FNA or EUS-B-FNA) and via trachea (EBUS-TBNA) and conventional bronchoscopy, including simulator–based training and assessment in the procedures. He is one of the leading forces behind the educational programme in EBUS made by the European Respiratory Society https://www.ersnet.org/education-and-professional-development/ers-certified-training-programmes/endobronchial-ultrasound-ebus-certified-training-programme/

Collection Overview

Lung cancer is the leading cause of cancer death worldwide. It is widely accepted that screening for lung cancer reduces cancer mortality. For this reason, pulmonologists can expect the referral of more patients with suspicious lung lesions. Therefore, invasive diagnostic pulmonary procedures are gaining interest.

In patients suspected of lung cancer, flexible bronchoscopy and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) are useful procedures for diagnosis and staging, especially in the case of a centrally located tumor. An EBUS endoscope placed into the esophagus and stomach (EUS-B) can be used to visualize and biopsy liver lesions, the left adrenal gland, and celiac nodes, which contributes to the staging of the disease. If the patient presents with a peripherally located suspicious lung lesion, guidance techniques (electromagnetic navigation bronchoscopy (ENB) supplemented with a radial mini-probe (p-EBUS) and/or fluoroscopy) can be helpful. An alternative to the latter is to perform a percutaneous lung biopsy guided by either computed tomography (CT), ultrasound, or fluoroscopy.

In the case of suspected lung cancer and pleural fluid, medical thoracoscopy may be considered. Thus, a wide spectrum of invasive procedures is available. The choice of technique is most often based on an assessment of positron emission tomography and computed tomography (PET-CT) scans. In this Methods Collection, we will focus on the main cornerstones for diagnosing and staging patients suspected of lung cancer, which are flexible bronchoscopy, EBUS, percutaneous lung biopsy, and medical thoracoscopy.

Articles

Systematic Bronchoscopy: the Four Landmarks Approach
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Systematic Bronchoscopy: the Four Landmarks Approach

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Cited by 4

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2023

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