Barrier Height Testing

Barrier Height Testing is a behavioral assay that measures how an animal responds to obstacles of systematically varied height, providing an index of locomotor ability, coordination, strength, and motivation. During the test, the subject encounters barriers that increase in height, and researchers record outcomes such as successful crossing, climbing behavior, hesitation, or avoidance under standardized conditions. These responses help distinguish changes in motor performance from altered motivation or exploratory behavior, making the assay useful for evaluating neurological function, motor impairment, learning, and the effects of disease or experimental treatments in behavioral research.

Barrier Height Testing - Related Videos

Research

JoVE Journal - Biology

Testing the Physiological Barriers to Viral Transmission in Aphids Using Microinjection

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Cited by 7 •

2008

Aphids are effective transmitters of plant viruses. Aphid microinjection of virus, the procedure we will show you today, is a technique allowing researchers to inject virus directly into the hemocoel of the aphid, bypassing the gut, one of the 2 major barriers for virus transmission in a circulative manner. The same technique is also used to inject dsRNA for RNAi.

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

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Cited by 26 •

2017

Multilayer microfluidic devices often involve the fabrication of master molds with complex geometries for functionality. This article presents a complete protocol for multi-step photolithography with valves and variable height features tunable to any application. As a demonstration, we fabricate a microfluidic droplet generator capable of producing hydrogel beads.

Education

JoVE Science Education - Psychology

Anxiety Testing

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2023

Anxiety is a commonly observed behavioral disorder that stems from fear. It is described as increased restlessness, or unpleasant feelings of fear over anticipated events. Experimenters often use rodent models to better understand anxiety disorders in humans. They use different paradigms, like exposing rodents to bright spaces or loud sounds, which are known to induce fear. These tests combined with other interventions such as surgery or drug-administration may assist researchers in pinpointing...

Tests on Wood

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA Wood is a ubiquitous material that has been used in construction from the earliest times. Wood is a renewable, sustainable material with great aesthetic value. Today, there are probably more buildings constructed with wood than any other structural material. Many of these buildings are singlefamily residences, but many larger apartment buildings, as well as commercial and industrial buildings,...

Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells

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Cited by 31 •

2017

The aim of the protocol is to present an optimized procedure for the establishment of an in vitro blood-brain barrier (BBB) model based on primary porcine brain endothelial cells (pBECs). The model shows high reproducibility, high tightness, and is suitable for studies of transport and intracellular trafficking in drug discovery.

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