Post-stroke Neurophysiology
Post-stroke Neurophysiology - Related Videos
08:23
Standing Neurophysiological Assessment of Lower Extremity Muscles Post-Stroke
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Cited by 4 •
2021
This protocol describes the process for performing a neurophysiological assessment of the lower extremity muscles, tibialis anterior and soleus, in a standing position using TMS in people post-stroke. This position provides a greater probability of eliciting a post-stroke TMS response and allows for the use of reduced stimulator power during neurophysiological assessments.
09:16
An Introduction to Neurophysiology
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2023
Neurophysiology is broadly defined as the study of nervous system function. In this field, scientists investigate the central and peripheral nervous systems at the level of whole organs, cellular networks, single cells, or even subcellular compartments. A unifying feature of this wide-ranging discipline is an interest in the mechanisms that lead to the generation and propagation of electrical impulses within and between neurons. This subject is important not only for our understanding of the...
02:59
Stereotactic Injection of Hydrogel into a Post-Stroke Mouse Model
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2025
Source: Wilson, K.L., et al. Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke. J. Vis. Exp. (2020)This video demonstrates the stereotaxic injection of a hydrogel into the stroke core of a post-stroke mouse, highlighting its role in scaffold formation that mimics the extracellular matrix, promotes cellular infiltration, and supports angiogenesis, underscoring its neurotherapeutic potential in stroke recovery.
![Autoradiographic Measurements of [<sup>14</sup>C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F53947.jpg%3Fv%3D2026-09-01%252006%253A32%253A11&w=750&q=75)
07:27
Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
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Cited by 1 •
2016
We present a protocol to measure [14C]-iodoantipyrine (IAP) uptake and assess the activation of neural substrates that are involved in central post-stroke pain (CPSP) in a rodent model.
11:06
A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation
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Cited by 9 •
2016
A novel low-cost human-machine interface for interactive post-stroke balance rehabilitation system is presented in this article. The system integrates off-the-shelf low-cost sensors towards volitionally driven electrotherapy paradigm. The proof-of-concept software interface is demonstrated on healthy volunteers.
FAQs
Changes in cortical excitability can modify how surviving brain regions respond during behavior. These shifts occur alongside tissue injury, altered blood flow, and disrupted communication between connected areas. As a result, the same behavioral task may require different neural processing after stroke, helping explain changes in movement, attention, language, memory, emotion, or social behavior.
Behavior depends on coordinated activity across connected neural regions, so stroke-related disruption can affect more than the damaged tissue itself. Impaired communication may contribute to distinct patterns of functional difficulty, while surviving networks can support compensation through reorganization. Studying these network-level changes helps researchers connect physiological disruption with observable behavioral outcomes.
Neuroplasticity allows surviving neural networks to reorganize after injury. This reorganization may support compensation when damaged circuits no longer function normally, although the resulting behavioral pattern can include both improvement and persistent impairment. Examining these changes helps researchers understand why recovery differs across functions such as movement, language, attention, memory, emotion, and social behavior.
Researchers measure brain activity and physiological responses while participants perform behavioral tasks. They then compare neural patterns with functional performance, such as changes in movement, attention, language, memory, emotion, or social behavior. This approach links nervous-system activity to observable outcomes and provides a structured way to examine how altered physiology relates to recovery.
Brain-activity measurements collected during behavior can reveal how physiological changes correspond to functional outcomes. They may show patterns associated with impairment, compensation, or reorganization in surviving networks. In research, these observations support evaluation of rehabilitation and may help identify biomarkers, meaning measurable biological features that could inform predictions about recovery or intervention needs.
Behavior provides a functional expression of altered neural processing after stroke. Examining performance alongside brain and nervous-system responses allows researchers to study how circuit injury and reorganization affect movement, attention, language, memory, emotion, and social interaction. This subject-specific connection supports rehabilitation research by relating measurable physiology to meaningful changes in everyday function.