Open-source Robot

An open-source robot is a programmable machine whose hardware designs, software, and documentation are openly available for inspection, modification, and sharing. It operates through coordinated control software, electronic components, sensors, and actuators that translate user-defined instructions into repeatable physical actions. In biochemistry, open-source robots can automate tasks such as liquid handling, sample preparation, reagent dispensing, and instrument control, helping researchers standardize experiments while reducing costs. Their adaptable designs support teaching, rapid prototyping, and collaborative method development, although reliable performance still depends on careful calibration, contamination control, and validation against established laboratory procedures.

Open-source Robot - Related Videos

Research

JoVE Journal - Neuroscience

Building An Open-source Robotic Stereotaxic Instrument

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Cited by 18 •

2013

This protocol includes the designs and software necessary to upgrade an existing stereotaxic instrument to a robotic (computer numeric controlled; CNC) stereotaxic instrument for around $1,000 (excluding a drill).

Insect-controlled Robot: A Mobile Robot Platform to Evaluate the Odor-tracking Capability of an Insect

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Cited by 18 •

2016

The capability to localize an odor source is necessary for insect survival and is expected to be applicable to artificial odor-tracking. The insect-controlled robot is driven by an actual silkmoth and enables us to evaluate the odor-tracking capability of insects through a robotic platform.

Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot

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Cited by 8 •

2021

Detailed protocol and three Python scripts are provided for operating an open-source robotic liquid handling system to perform semi-automated protein sample preparation for mass spectrometry experiments, covering detergent removal, protein digestion, and peptide desalting steps.

SSVEP-based Experimental Procedure for Brain-Robot Interaction with Humanoid Robots

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Cited by 12 •

2015

The overall goal of this method is to establish an SSVEP-based experimental procedure by integrating multiple software programs to enable the study of brain-robot interaction with humanoid robots, which is prospective in assisting the sick and elderly as well as performing unsanitary or dangerous jobs.

Research

JoVE Journal - Neuroscience
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Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches

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Cited by 49 •

2014

We describe a protocol for using insect antennae in the form of electroantennograms (EAGs) on autonomous robots. Our experimental design allows stable recordings within a day and resolves individual odor patches up to 10 Hz. The efficiency of EAG sensors for olfactory searches is demonstrated in driving a robot toward an odor source.

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