Tetrabutylammonium Bromide

Tetrabutylammonium bromide is a quaternary ammonium salt used as a phase-transfer catalyst, electrolyte, and source of tetrabutylammonium ions in chemical and bioengineering research. Its four butyl groups give the cation compatibility with organic phases, while bromide provides a mobile counterion; together, they help transport charged reactants across poorly mixed aqueous and organic layers, increasing interfacial contact and reaction efficiency. This behavior supports biphasic synthesis, extraction, ion-pair formation, and preparation of functional materials relevant to biosensors, drug-delivery systems, and biomaterials. Careful control of concentration, solvent, temperature, and residual salt is important when biological components or downstream cell-based applications are involved.

Tetrabutylammonium Bromide - Related Videos

Research

JoVE Journal - Chemistry

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of Phosphorus(I)

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Cited by 4 •

2016

The synthesis of a triphosphenium bromide salt is described and its use as a P+ transfer agent is outlined by reactions with an N-heterocyclic carbene and an anionic bisphosphine, yielding an NHC-stabilized P(I) cation and a P(I) containing zwitterion, respectively.

DNA Electrophoresis Using Thiazole Orange Instead of Ethidium Bromide or Alternative Dyes

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Cited by 5 •

2019

Here, we present a protocol to use thiazole orange for the detection of DNA in gel electrophoresis experiments. The use of thiazole orange allows elimination of ethidium bromide, and fluorescence detection can be achieved with either UV or blue light.

Whole-Genome Deoxyribonucleic Acid Extraction from Mycobacterium Species via the Cetyltrimethylammonium Bromide Technique

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2025

This protocol describes the CTAB method for extracting high-quality DNA from mycobacteria, overcoming challenges posed by their tough, mycolic acid-rich cell walls. The process involves enzymatic digestion, cell lysis with CTAB, and DNA purification through organic extraction and ethanol precipitation. This method produces DNA suitable for molecular studies and is reliable for mycobacterial research.

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

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2019

A simple and practical protocol for the efficient conjugate addition of functionalized monoorganozinc bromides to cyclic α,β-unsaturated carbonyls to furnish all-carbon quaternary centers was developed.

Research

JoVE Journal - Medicine
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Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

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Cited by 6 •

2017

We demonstrate the semi-automated radiochemical synthesis of [18F]3F4AP and quality control procedures.

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