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Automated Radiochemical Synthesis of [¹⁸F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

JoVE Journal
Medicine

This content is Free Access.

JoVE Journal Medicine

Automated Radiochemical Synthesis of [¹⁸F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

Automated Radiochemical Synthesis of [¹⁸F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

DOI:

10.3791/55537-v

•

11:03 min

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May 29, 2017

•

Pedro Brugarolas, Mohammed Bhuiyan, Anna Kucharski, Richard Freifelder

¹Department of Neurology,The University of Chicago, ²Department of Radiology,The University of Chicago

Chapters

00:05Title
01:10Synthesis Module and Reagent Preparation
03:58Synthesis of [¹⁸F]3FAP
06:17Quality Control
08:33Results: The Radiochemical Synthesis of [¹⁸F]3FAP
09:28Conclusion

Summary

Automatic Translation

We demonstrate the semi-automated radiochemical synthesis of [¹⁸F]3F4AP and quality control procedures.

Tags

Keywords: [18F]3F4AP PET Tracer Demyelinating Diseases Automated Radiochemical Synthesis Fluorine-18 Hydrogenation Solid Phase Extraction HPLC

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