Alb3 Translocase

Alb3 translocase is a chloroplast thylakoid-membrane protein insertase that enables selected newly synthesized proteins to become embedded in the membrane, supporting photosynthetic function. It belongs to the conserved YidC/Oxa1/Alb3 family and provides a hydrophilic passage within the lipid bilayer through which substrate transmembrane helices are recognized, guided, and laterally released into the membrane. In plants, Alb3 works with the chloroplast signal recognition particle pathway to insert light-harvesting chlorophyll a/b-binding proteins, whose arrangement helps build photosynthetic antenna complexes. Studying this translocase clarifies how chloroplasts assemble membrane protein complexes and helps explain defects in thylakoid formation, photosynthetic efficiency, and plant development.

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