Alveolar Glands
Alveolar Glands - Related Videos
11:26
Harvesting Murine Alveolar Macrophages and Evaluating Cellular Activation Induced by Polyanhydride Nanoparticles
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Cited by 16 •
2012
Herein, we describe protocols for harvesting murine alveolar macrophages, which are resident innate immune cells in the lung, and examining their activation in response to co-culture with polyanhydride nanoparticles.
09:36
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
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Cited by 61 •
2010
Our protocol describes how to dissect the rat abdominal mammary gland and how to prepare mammary gland whole mounts. It also describes how to analyze mammary gland morphology using three end-points (number of terminal end buds, epithelial elongation and differentiation) and to use these results to predict mammary cancer risk in rats which were exposed to dietary modifications in utero or during prepuberty.
06:14
Isolation of Alveolar Type II Epithelial Cells from Neonatal, Juvenile, and Adult Murine Lungs Adaptable to Infectious Experimental Settings
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2025
This protocol presents a flow cytometry-based method to isolate viable alveolar type II epithelial cells (AECII) from neonatal, juvenile, or adult murine lungs (infected or non-infected). This approach enables downstream molecular and/or functional studies of AECII to identify their roles during lung inflammation and infection.
09:22
Sectioning Mammary Gland Whole Mounts for Lesion Identification
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Cited by 13 •
2017
We developed a method to successfully remove, process, section, and stain, for histopathological evaluation, mammary tissue that had originally been fixed on slides as whole mounts. This method may promote the collection and evaluation of mammary gland whole mounts in reproductive and developmental test guideline studies.
09:04
Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy
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Cited by 3 •
2014
A method to evaluate the ability of isolated mouse alveolar macrophages to control the growth of phagocytosed Aspergillus spores by confocal microscopy.
FAQs
The epithelial cells synthesize the gland’s secretory product and release it into the central lumen of each alveolus. From there, the duct system provides an organized route toward a body surface or cavity. This arrangement links cellular production with directional export, allowing gland architecture to support external secretion rather than simply retaining material within the tissue.
Simple and compound arrangements describe how alveolar secretory units are organized within a gland. This structural distinction helps relate the pattern of secretory tissue to the extent of the duct system and to glandular specialization. Comparing these arrangements gives biologists a way to connect overall architecture with how tissues are organized for secretion.
The duct system connects secretory units with the destination where their products are released, such as a body surface or cavity. It therefore provides more than structural support: it establishes the pathway that turns cellular synthesis into external secretion. Examining this connection helps explain how tissue organization directs the movement of glandular material.
Their organization provides a framework for examining how secretory tissues form, become specialized, and function. Researchers can relate epithelial cells, alveoli, lumens, and ducts to changes in gland structure during normal development or physiological activity. This perspective helps connect cellular organization with the broader performance of secretory organs.
Because secretion depends on coordinated epithelial organization, lumens, and ducts, changes in these features can be examined as part of pathological analysis. Comparing gland architecture with its normal organization may help identify structural alterations associated with disease-related changes. The approach focuses on how disrupted organization could affect secretory tissue function.
Alveolar glands illustrate how the arrangement of cells and tissue compartments supports a specialized function. Their epithelial cells, lumens, and ducts can be considered together to study the relationship between microscopic organization and secretion. This makes them useful for connecting basic cell biology with tissue function, glandular specialization, development, and pathology.