Disc Space Preparation

Disc space preparation is a procedure that clears and shapes the intervertebral disc space to support spinal repair, reconstruction, or fusion. It typically involves removing degenerated disc material and preparing the adjacent vertebral endplates while preserving sufficient structural bone for implant support. Careful preparation creates a stable interface for graft material or an interbody device and helps restore appropriate spacing between vertebrae. In biological and clinical research, studying this process clarifies how tissue removal, mechanical stability, and bone integration influence healing outcomes. These principles also inform the development of biomaterials, surgical techniques, and regenerative strategies for treating disc degeneration.

Disc Space Preparation - Related Videos

Research

JoVE Journal - Bioengineering
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In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

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Cited by 16 •

2012

Simple and reproducible procedures are described for making three structurally distinct collagen assemblies from a common commercially available Type I collagen monomer. Native type, fibrous long spacing or segmental long spacing collagen can be constructed by varying the conditions to which the 300 nm long and 1.4 nm diameter monomer building block is exposed.

Research

JoVE Journal - Biology
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Generation, Purification, and Characterization of Cell-invasive DISC1 Protein Species

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Cited by 13 •

2012

The generation, purification and cell invasion of intracellular, cytoplasmic full length DISC1 protein aggresomes from cell cultures and of a labeled, multimeric recombinant DISC1 protein fragment in E. coli are described. Cell invasiveness is shown for recipient cells in cell culture and for neurons in vivo after stereotactical brain inoculation.

Education

JoVE Core - Calculus

Space Curves

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2026

A space curve describes the path followed by a particle moving through three-dimensional space. Unlike plane curves, which are confined to two coordinates, space curves require three coordinate functions. If t is a parameter, the position of the particle is represented by the vector function\begin{equation*}\mathbf{r}(t)=\langle x(t),y(t),z(t)\rangle,\end{equation*}where x(t), y(t), and z(t) are differentiable functions of t. As t varies over an interval, the endpoints of the position vectors...

Space Trusses

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2025

A space truss is a three-dimensional counterpart of a planar truss. These structures consist of members connected at their ends, often utilizing ball-and-socket joints to create a stable and versatile framework. The space truss is widely used in various construction projects due to its adaptability and capacity to withstand complex loads. At the core of a space truss lies the fundamental unit known as the tetrahedron. This structure is composed of six members that form a three-dimensional shape...

State Space Representation

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2024

The frequency-domain technique, commonly used in analyzing and designing feedback control systems, is effective for linear, time-invariant systems. However, it falls short when dealing with nonlinear, time-varying, and multiple-input multiple-output systems. The time-domain or state-space approach addresses these limitations by utilizing state variables to construct simultaneous, first-order differential equations, known as state equations, for an nth-order system. Consider an RLC circuit, a...

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