Disease Vector Control
Disease Vector Control - Related Videos
08:33
Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector
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Cited by 12 •
2016
This manuscript describes how viral vector-mediated local gene delivery provides an attractive way to express transgenes in the central nervous system. The protocol outlines all crucial steps to perform a viral vector injection in the substantia nigra of the rat to develop a viral vector-based animal model for Parkinson's disease.
10:21
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
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Cited by 13 •
2007
In this interview, Jason Rasgon explains the concept of genetic drive and the characteristics of an effective gene drive system. The use of the endosymbiotic bacterium, Wolbachia pipientis, as a means to spread genes through mosquito populations, is hypothesized.
10:49
Visualizing Efficacy of Pesticides Against Disease Vector Mosquitoes in the Field
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Cited by 3 •
2019
The efficacy of public health pesticides targeting nuisance and disease-vector insects is not uniform across different ecological zones. Here we present a system of techniques using captive vector insects as sentinels for pesticide efficacy to derive electronic maps supporting the standard evaluation of pesticides across multiple environments.
05:13
A Viral Vector Injection into the Rat Substantia Nigra for Neurodegenerative Disease Modeling
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2025
This video demonstrates the process of injecting a viral vector into the rat substantia nigra to model Parkinson's disease. It outlines the steps for preparing the rat, microinjecting the viral vector into the substantia nigra, and the recovery procedure.
09:21
Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors
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Cited by 35 •
2019
Here, we describe an efficient and reproducible strategy to produce, titer, and quality-control batches of adeno-associated virus vectors. It allows the user to obtain a vector preparation with high-titer (≥1 x 1013 vector genomes/mL) and a high purity, ready for in vitro or in vivo use.
FAQs
Interventions reduce transmission by disrupting either the vector’s life cycle or its contact with hosts. Removing breeding sites and applying larvicides can reduce vector development, while insecticides and treated bed nets limit contact with people. These mechanisms address different points in transmission, so combining them can provide broader protection than relying on a single intervention.
Vector ecology determines where vectors develop, how they interact with hosts, and which intervention points are practical. Insecticide resistance can reduce the effectiveness of chemical measures, making a fixed strategy less reliable over time. Programs therefore need to adapt their control choices to local transmission patterns and vector characteristics rather than applying the same approach everywhere.
Environmental measures alter conditions that support vectors, such as by removing breeding sites. Chemical measures use larvicides or insecticides, whereas biological control introduces agents that affect vector populations. Behavioral measures reduce human-vector contact, including through insecticide-treated bed nets. Because each category acts through a different pathway, integrated programs can address both vector abundance and exposure.
Planning begins by considering the vector’s ecology, the pathogen’s transmission pattern, and the local conditions that support contact between vectors and hosts. Programs can then combine measures such as breeding-site removal, larvicide or insecticide use, biological control, and treated bed nets. Ongoing surveillance helps assess transmission and supports adaptation when conditions or resistance change.
The source identifies several practical tools: environmental removal of breeding sites, larvicides that target developing vectors, insecticides, biological control agents, and insecticide-treated bed nets. These tools serve different purposes. Some reduce vector development or abundance, while others prevent contact with hosts, allowing control programs to select complementary measures for the relevant vector and setting.
In biology and public health, vector control supports surveillance by linking intervention choices to vector ecology and pathogen transmission patterns. It is used in prevention efforts for diseases including malaria, dengue, and Lyme disease. Combining multiple strategies can help reduce opportunities for transmission while programs monitor changing conditions, including the emergence of insecticide resistance.