Gray Rami Communicantes

Gray rami communicantes are short nerve branches that connect the sympathetic trunk to spinal nerves, carrying postganglionic sympathetic fibers throughout the body. Their gray appearance reflects the predominance of unmyelinated axons; after synapsing in a sympathetic chain ganglion, sympathetic neurons return through these rami to join spinal nerves and travel with their dorsal and ventral branches, or continue to nearby vessels. This arrangement distributes autonomic signals to sweat glands, arrector pili muscles, and vascular smooth muscle, supporting thermoregulation, skin responses, and control of regional blood flow. Understanding gray rami communicantes helps explain how the sympathetic nervous system reaches structures supplied by spinal nerves.

Gray Rami Communicantes - Related Videos

Research

JoVE Journal - Medicine

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy

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Cited by 2 •

2019

We present a protocol for selective chemical lumbar sympathectomy (CLS), which inactivates only gray rami communicantes and not the sympathetic trunk. Selective CLS can help achieve therapeutic efficacy in vasodilation, sweat reduction, and pain relief that are comparable to conventional CLS, and serious complications, particularly ureteropelvic damages, can be reduced.

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2026

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JoVE Journal - Neuroscience
Free Sample

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Cited by 7 •

2008

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2023

CRISPR-Cas technologies have revolutionized the field of genome editing. However, finding and isolating the desired germline edit remains a major bottleneck. Therefore, this protocol describes a robust method for quickly screening F0 CRISPR-injected zebrafish sperm for germline edits using standard PCR, restriction digest, and gel electrophoresis techniques.

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