Heart Dissection

Heart dissection is a biological method for examining the heart’s external and internal anatomy, helping students and researchers understand how its structures support circulation. By carefully opening the chambers and tracing major blood vessels, the procedure reveals the atria, ventricles, septum, valves, and differences in muscular wall thickness; these features can then be related to the direction of blood flow through the pulmonary and systemic circuits. In biology education, heart dissection connects anatomical observations with cardiac function and cardiovascular physiology. It also provides a foundation for comparing hearts across species and for recognizing structural changes associated with disease or developmental differences.

Heart Dissection - Related Videos

Research

JoVE Journal - Biology

Immunostaining of Dissected Zebrafish Embryonic Heart

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Cited by 35 •

2012

A rapid way to conduct immunostaining of zebrafish embryonic heart is described. Compared to the whole mount immunostaining approach, this method dramatically increases the penetration of the antibodies, which allows obtaining high resolution images that reveal cellular/subcellular structures in the heart within a much reduced processing time.

Heart Dissection: A Method to Observe Zebrafish Cardiac Development

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2023

This video describes a technique of isolating the heart from a zebrafish at multiple developmental stages to study cardiac development, maturation, and ageing.

Heart Dissection in Larval, Juvenile and Adult Zebrafish, Danio rerio

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Cited by 19 •

2011

A clear, standardized method for dissection and isolation of the zebrafish heart at multiple developmental stages are described. Annotation and quantification techniques are also discussed.

Research

JoVE Journal - Medicine
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Implantation of Total Artificial Heart in Congenital Heart Disease

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Cited by 40 •

2014

This is a case report of a patient with congenitally corrected transposition of the great arteries (CCTGA) who received a total artificial heart (TAH) as a bridge to heart transplant. The TAH was successfully implanted with modifications to accommodate the patient's congenitally malformed heart.

A Novel Ex vivo Culture Method for the Embryonic Mouse Heart

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Cited by 12 •

2013

Developmental studies in the mouse are hampered by the inaccessibility of the embryo during gestation. To promote the long-term culture of the embryonic heart at late stages of gestation, we developed a protocol in which the excised heart is cultured in a semi-solid, dilute Matrigel.

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