Limbic System

The limbic system is a network of interconnected brain structures that helps regulate emotion, memory, motivation, learning, and basic survival behaviors. It coordinates information through circuits involving regions such as the amygdala, hippocampus, hypothalamus, and cingulate cortex, linking sensory experiences with autonomic and endocrine responses. By shaping fear, reward, stress, and the formation or retrieval of memories, the limbic system influences behavior and adaptation to changing conditions. Studying this network provides important insight into biological processes underlying emotional regulation, decision-making, stress responses, and neurological or psychiatric disorders.

Limbic System - Related Videos

Education

JoVE Core - Anatomy and Physiology

Functional Brain Systems: Limbic System

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2025

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...

Research

JoVE Journal - Behavior

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

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Cited by 1 •

2015

This paper describes how to use the emotional oddball task and fMRI to measure brain activation in children and adolescents at familial high risk for schizophrenia (FHR). FMRI was used to measure differences in fronto-striato-limbic regions during an emotional oddball task. Children with FHR exhibited abnormal functional activation during adolescence.

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

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2025

The protocol introduces an innovative method for analyzing and visualizing behaviors associated with pentylenetetrazole-induced seizures in mice. This approach extends beyond traditional Racine's scores, providing a more comprehensive evaluation of the diversity and temporal dynamics of ictal behaviors.

Research

JoVE Journal - Neuroscience
Free Sample

A Method for High Fidelity Optogenetic Control of Individual Pyramidal Neurons In vivo

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Cited by 2 •

2013

The recent development of neuroscience tools that combine genetics and optics, termed "optogenetics", enables control over neural circuit activity with an unprecedented level of spatial and temporal resolution. Here we provide a protocol for integrating in vivo recording with optogenetic manipulation of genetically-defined subsets of prefrontal cortical and subicular pyramidal neurons.

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain

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Cited by 2 •

2017

This paper demonstrates the effective use of a fiber dissection method to reveal the superficial white matter tracts and periventricular structures of the human brain, in three-dimensional space, to aid student comprehension of ventricular morphology.

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