Liquid Marble Formation

Liquid marbles are liquid droplets wrapped in a shell of hydrophobic particles, creating mobile, nonwetting microreactors that isolate their contents from surrounding surfaces. They form when a water-based droplet contacts a suitable powder and rolls across it, allowing particles to adsorb at the liquid-air interface and stabilize the droplet through surface-energy effects. In biology, liquid marble formation supports small-scale cell culture, microbial growth, biochemical assays, and controlled studies of compartmentalized reactions, while the protective coating can limit direct contact, evaporation, and contamination.

Liquid Marble Formation - Related Videos

Research

JoVE EoE - Large Animal Models

Liquid Marble Microbioreactor System: A 3D Culture Protocol for Encapsulation of Porcine Oocytes

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2025

In this video, we describe a protocol for the encapsulation of porcine oocytes in hydrophobic microbioreactors.

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

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Cited by 402 •

2013

Disease, head injury, genetic modifications, and treatment of mice with drugs can have profound effects on behavior. Utilizing well-characterized and validated approaches such as marble burying and nestlet shredding, compulsive-like behaviors can be documented accurately in mice as models of human obsessive-compulsive disorder and autism spectrum disorder.

Education

JoVE Science Education - Engineering

Efficiency of Liquid-liquid Extraction

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2023

Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Liquid-liquid extraction (LLE) is a separation technique used instead of distillation when either: (a) the relative volatilities of the compounds to be separated are very similar; (b) one or more of the mixture components are temperature sensitive even near ambient conditions; (c) the distillation would require a very low pressure or a very high distillate/feed...

Solution Formation

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2020

There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride. This selective solubility...

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

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Cited by 9 •

2017

This study presents a methodology to prepare 3D, biodegradable, foam-like cell scaffolds based on biocompatible side-chain liquid crystal elastomers (LCEs). Confocal microscopy experiments show that foam-like LCEs allow for cell attachment, proliferation, and the spontaneous alignment of C2C12s myoblasts.

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