Lymph Node Dissection
Lymph Node Dissection - Related Videos
16:48
Dissection and 2-Photon Imaging of Peripheral Lymph Nodes in Mice
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Cited by 20 •
2007
Two-photon imaging has uncovered lymphocyte motility and cellular interactions within the lymph node under basal conditions and durring an immune response 1. Here, we demonstrate adoptive transfer of T cells, isolation of lymph nodes, and imaging motility of CD4+ T cells in the explanted lymph node.
08:06
Lymph Node Exam
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2023
Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA The lymphatic system has two main functions: to return extracellular fluid back to the venous circulation and to expose antigenic substances to the immune system. As the collected fluid passes through lymphatic channels on its way back to the systemic circulation, it encounters multiple nodes consisting of highly concentrated clusters of...
04:36
Murine Superficial Lymph Node Surgery
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Cited by 10 •
2012
To follow the progression of an immune response over time within the same mouse, lymph nodes can be sequentially removed by surgery. Here, we describe how this technique can be performed.
02:16
A Dissection Method to Harvest Murine Popliteal Draining Lymph Nodes for Ex Vivo Imaging
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2025
This video demonstrates a dissection technique to harvest popliteal draining lymph nodes from the mouse hind legs. Lymph nodes play a critical role in bridging innate and adaptive immunity, and harvesting intact lymph nodes — with a preserved tissue structure and cellular viability — can help study local and systemic immune responses.
11:49
Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
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2026
This study describes a standardized surgical procedure for single-port endoscopic axillary lymph node dissection without liposuction in breast cancer. Indicated for patients with biopsy-confirmed nodal metastasis or positive sentinel lymph nodes, the technique emphasizes preservation of critical structures, particularly the intercostobrachial nerve, to reduce postoperative morbidity and optimize functional recovery.
FAQs
Their location makes them relevant to the route by which tumor cells may travel through the lymphatic system. Examining these regional nodes can show whether metastatic cells have reached tissue near the primary tumor, providing evidence about localized disease spread and helping clinicians interpret the biological behavior of the cancer.
Histopathological analysis examines the excised tissue for metastatic cells. The resulting findings distinguish nodes with detectable tumor involvement from those without identified metastasis, giving clinicians evidence for disease staging and subsequent treatment decisions. In this way, laboratory examination converts surgically obtained tissue into information about regional cancer spread.
The procedure provides direct information about the sampled regional lymphatic tissue, rather than relying only on the appearance of the primary tumor. Detecting metastatic cells in those nodes supports regional spread, while their absence provides information about the examined nodes. These findings help clarify disease extent but describe the sampled region specifically.
Removing lymphatic tissue can disrupt normal lymphatic drainage. When fluid movement through that system is affected, lymphedema becomes a possible complication. This risk explains why patient selection requires care and why monitoring after the operation matters. Clinical teams must weigh the diagnostic or regional-control value of node removal against potential drainage-related harm.
The workflow has an operative phase and a pathology phase. Clinicians first identify lymphatic tissue associated with the primary tumor, remove the selected nodes, and send the specimens for histopathological analysis. The pathology findings are then used to assess metastatic involvement, clarify disease spread, and support staging or treatment decisions.
Its principal use is in situations where examining regional lymphatic tissue can clarify cancer spread or contribute to disease treatment. The procedure may therefore support staging decisions, guide treatment planning, and provide regional disease control. Because lymphatic disruption can cause lymphedema, clinicians must consider patient selection and follow-up needs.
By linking a primary tumor with nearby lymphatic tissue and examining that tissue for metastatic cells, the procedure provides biological evidence about a possible route of tumor spread. It connects the anatomy of regional lymph nodes with disease findings, making the lymphatic system relevant to both cancer investigation and medical decision-making.
The operation can produce several clinically relevant outcomes: tissue for histopathological evaluation, evidence about regional metastatic involvement, and information used in staging and treatment planning. It may also contribute to regional disease control. At the same time, disruption of lymphatic drainage creates a potential complication, so outcomes include the need for continued monitoring.