Systolic Diastolic Pressure

Systolic and diastolic pressure are the two values used to describe blood pressure, the force that circulating blood exerts against arterial walls and an important indicator of cardiovascular function. Systolic pressure is the peak pressure produced when the heart’s ventricles contract, whereas diastolic pressure is the lower pressure maintained while the ventricles relax and refill between beats. Together, these measurements reflect how the heart pumps and how blood vessels resist flow. Studying systolic and diastolic pressure helps biologists and clinicians assess circulation, identify abnormal cardiovascular conditions, and evaluate how factors such as vascular resistance and cardiac performance affect health.

Systolic Diastolic Pressure - Related Videos

Research

JoVE Journal - Medicine

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

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Cited by 1 •

2020

We describe the creation of a rat model of pressure overload induced moderate remodeling and early systolic dysfunction where signal transduction pathways involved in the initiation of the remodeling process are activated. This animal model will aid in identifying molecular targets for applying early therapeutic anti-remodeling strategies for heart failure.

Education

JoVE Science Education - Engineering

Noninvasive Blood Pressure Measurement Techniques

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2023

Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

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Cited by 8 •

2014

Accurate, causality-based quantification of global diastolic function has been achieved by kinematic modeling-based analysis of transmitral flow via the Parametrized Diastolic Filling (PDF) formalism. PDF generates unique stiffness, relaxation, and load parameters and elucidates 'new' physiology while providing sensitive and specific indexes of dysfunction.

Research

JoVE Journal - Biology
Free Sample

Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method

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Cited by 175 •

2009

The CODA 8-Channel High Throughput Non-Invasive Blood Pressure system measures the blood pressure in up to 8 mice or rats simultaneously. This tail-cuff system uses Volume Pressure Recording (VPR) to measure the blood pressure by determining the tail blood volume.

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

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Cited by 17 •

2013

A specific and rapid protocol to simultaneously investigate right heart function, lung inflammation, and the immune response is described as a learning tool. Video and figures describe physiology and microdissection techniques in an organized team-approach that is adaptable to be used for small to large sized studies.

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