Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Wen-Chi Chen; Sung-Hyun Park; Carol Hoffman; Cecil Philip; Linda Robinson; James West; Gabriele Grunig

doi:10.3791/50023

Journal

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Immunology and Infection

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Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

25,064 Views

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10:20 min

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January 16, 2013

DOI:

10.3791/50023-v

DOI:

10.3791/50023-v

•

10:20 min

January 16, 2013

•

5 Views

Wen-Chi Chen*¹, Sung-Hyun Park*¹, Carol Hoffman¹, Cecil Philip¹, Linda Robinson², James West², Gabriele Grunig^1,3

¹Department of Environmental Medicine,New York University School of Medicine, Tuxedo, ²Division of Allergy, Pulmonary, & Critical Care Medicine, Department of Medicine,Vanderbilt University Medical Center, ³Division of Pulmonary Medicine,New York University School of Medicine

Summary

A specific and rapid protocol to simultaneously investigate right heart function, lung inflammation, and the immune response is described as a learning tool. Video and figures describe physiology and microdissection techniques in an organized team-approach that is adaptable to be used for small to large sized studies.