Ventral Adhesive Disk

The ventral adhesive disk is a specialized attachment organelle in Giardia trophozoites that enables the parasite to remain attached to the intestinal epithelium. Its concave, microtubule-supported structure contacts the host surface through adhesive interactions and fluid forces generated as intestinal contents move around the cell. This attachment helps Giardia resist physical removal while colonizing the gut, making the disk important for understanding parasite biology and giardiasis. Studying its cytoskeletal architecture, associated proteins, and adhesion mechanism can clarify how single-celled organisms interact with host tissues and may guide research on therapies that disrupt parasite attachment.

Ventral Adhesive Disk - Related Videos

Research

JoVE Journal - Bioengineering

Visualizing Adhesion Formation in Cells by Means of Advanced Spinning Disk-Total Internal Reflection Fluorescence Microscopy

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2019

An advanced microscope that permit fast and high-resolution imaging of both, the isolated plasma membrane and the surrounding intracellular volume, will be presented. The integration of spinning disk and total internal reflection fluorescence microscopy in one setup allows live imaging experiments at high acquisition rates up to 3.5 s per image stack.

Education

JoVE Core - Biology

Adhesion

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2019

Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules. Capillary action is a result of water’s adhesive tendencies. When a narrow glass...

Research

JoVE Journal - Bioengineering
Free Sample

20 mJ, 1 ps Yb:YAG Thin-disk Regenerative Amplifier

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Cited by 1 •

2017

A protocol for the operation of a high-energy, high-power optical parametric chirped pulse amplifier pump source based on an Yb:YAG thin-disk regenerative amplifier is presented here.

Faraday Disk Dynamo

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2023

A Faraday disk dynamo is a DC generator, producing an emf that is constant in time. It consists of a conducting disk that rotates with a constant angular velocity in the magnetic field, perpendicular to the disk's plane. The rotation of the disk causes a change in magnetic flux, which induces an emf, causing opposite charges to develop on the rim and in the center of the disk. The polarity of the induced emf can be determined by the direction of the magnetic field and the direction of the...

Co-culturing of Ventral Hippocampal and Nucleus Accumbens

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2025

This video demonstrates the process of preparing ventral hippocampal and nucleus accumbens tissues from mouse brains for co-culture. Neurons extend projections to form synaptic connections between the ventral hippocampal and nucleus accumbens tissues. This method allows studying neuronal interactions between these two brain regions, offering insights into cognition, behavior, and neurological disorders.

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