Ventricular Systolic Diastolic

Ventricular systole and diastole are the two alternating phases of the cardiac cycle that enable the heart to pump and refill with blood. During systole, ventricular muscle contracts, pressure rises, atrioventricular valves close, and blood is ejected through the pulmonary and aortic semilunar valves; during diastole, the ventricles relax, pressure falls, semilunar valves close, and blood flows through open atrioventricular valves to refill them. Understanding these phases helps explain cardiac output, blood pressure, and the timing of heart sounds. Measurements from electrocardiography, echocardiography, and pressure monitoring use ventricular timing to assess normal function and identify cardiovascular dysfunction.

Ventricular Systolic Diastolic - Related Videos

Research

JoVE Journal - Medicine

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

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Cited by 1 •

2019

Here we describe and compare two positions for obtaining the apical four-chamber view in mice. These positions enable the quantification of the right ventricular function, provide comparable results, and can be used interchangeably.

Research

JoVE Journal - Medicine
Free Sample

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

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Cited by 34 •

2013

This article describes procedures for implanting a novel hydrogel in failing hearts and quantifying its effect on left ventricular wall stress and function. These procedures have been successfully applied in dogs and humans.

Assessment of Sarcoplasmic Reticulum Calcium Reserve and Intracellular Diastolic Calcium Removal in Isolated Ventricular Cardiomyocytes

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Cited by 18 •

2017

Intracellular calcium recycling plays a critical role in regulation of systolic and diastolic function in cardiomyocytes. Here, we describe a protocol to evaluate sarcoplasmic reticulum Ca2+ reserve and diastolic calcium removal function in cardiomyocytes by a calcium imaging system.

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

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Cited by 8 •

2014

Accurate, causality-based quantification of global diastolic function has been achieved by kinematic modeling-based analysis of transmitral flow via the Parametrized Diastolic Filling (PDF) formalism. PDF generates unique stiffness, relaxation, and load parameters and elucidates 'new' physiology while providing sensitive and specific indexes of dysfunction.

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

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Cited by 17 •

2013

A specific and rapid protocol to simultaneously investigate right heart function, lung inflammation, and the immune response is described as a learning tool. Video and figures describe physiology and microdissection techniques in an organized team-approach that is adaptable to be used for small to large sized studies.

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