Neuroendoscopic Surgery
Neuroendoscopic Surgery - Related Videos
12:13
Considerations for Rodent Surgery
0 Views •
2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...
08:28
Rodent Stereotaxic Surgery
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2023
Stereotaxic (or stereotactic) surgery is a method used to manipulate the brain of living animals. This technique allows researchers to accurately target deep structures within the brain through the use of a stereotaxic atlas, which provides the 3D coordinates of each area with respect to anatomical landmarks on the skull. After the skull is exposed, anesthetized animals are mounted on a specialized instrument known as a stereotaxic frame, which enables the precise placement of experimental...
00:08
Survivable Stereotaxic Surgery in Rodents
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Cited by 50 •
2008
The monitoring of extracellular neurotransmitter levels in distinct brain regions of freely moving animals offers insights on the link between neurotransmitter release and behavior. In vivo microdialysis coupled with electrochemical detection provides excellent anatomical and chemical resolution; and information on how basal neurotransmission is altered by pharmacological or physiological manipulations.
10:29
Principles of Rodent Surgery for the New Surgeon
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Cited by 56 •
2011
Before attempting surgery, a new surgeon should have training in basic surgical techniques and concepts. This article will present basic surgical considerations with an emphasis on rodents.
04:36
Murine Superficial Lymph Node Surgery
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Cited by 10 •
2012
To follow the progression of an immune response over time within the same mouse, lymph nodes can be sequentially removed by surgery. Here, we describe how this technique can be performed.
FAQs
An endoscope combines a camera and light source to provide magnified views of the brain and ventricular system. Specialized instruments pass through or alongside the device, allowing the operator to act while viewing the target. This coordinated access supports targeted tissue sampling, lesion removal, or restoration of cerebrospinal fluid flow without relying on a large surgical opening.
Restoring cerebrospinal fluid flow addresses obstruction within the ventricular system, an issue that can accompany selected brain tumors. Under direct endoscopic visualization, instruments can be used to reestablish that flow. In cancer-related studies, this capability links management of a tumor-associated complication with assessment of a less invasive surgical approach.
Targeted biopsy can provide tumor tissue for molecular analysis, not merely a visual impression of a lesion. That specimen gives cancer researchers material to examine tumor characteristics while the procedure also contributes to diagnosis and management. Combining direct visualization with tissue acquisition makes neuroendoscopic approaches relevant to studies connecting surgical access with tumor biology.
The approach uses the endoscope to visualize the relevant brain or ventricular region, with its camera and light source transmitting a magnified image. Specialized instruments are then introduced through or alongside the endoscope for the selected task, such as obtaining tissue, removing a lesion, or restoring fluid flow. The task depends on the clinical target.
In cancer research, the technique is relevant to selected brain tumors when investigators need tissue, tumor treatment, or assessment of obstructive hydrocephalus. It supports both clinical management and research questions: tissue can be used for molecular analysis, while the procedure provides an opportunity to evaluate outcomes associated with less invasive neuro-oncologic approaches.
Researchers can evaluate more than whether a lesion was reached. Neuroendoscopic work can yield tissue for molecular analysis, document treatment of a lesion, and show whether obstructed cerebrospinal fluid flow was addressed. Together, these outcomes help connect surgical technique with diagnostic information, tumor management, and the development of less invasive strategies in neuro-oncology.