Close Contact

Close contact is a public health and clinical term describing interaction with an infected person that creates a meaningful risk of exposure to a transmissible pathogen. Risk depends on factors such as proximity, duration, ventilation, and the route of transmission, including inhalation of respiratory particles, contact with infectious secretions, or direct skin-to-skin spread. Clinicians and public health teams use close-contact criteria for exposure assessment, contact tracing, testing recommendations, monitoring, and decisions about isolation or preventive treatment. Because transmission patterns differ among pathogens, the definition is adapted to the infection, setting, and current public health guidance.

Close Contact - Related Videos

Education

JoVE Core - Physics

Contact Angle

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2023

When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces. The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive force...

Research

JoVE Journal - Immunology and Infection

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

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Cited by 2 •

2022

Contact hypersensitivity (CHS) is a murine experimental model of allergic contact dermatitis (ACD). CHS is based on sensitization with reactive hapten by painting the shaved skin of the chest and abdomen, with a subsequent ear skin challenge with a diluted hapten, causing a swelling reaction that is assessed in various ways.

Larval Contact Assay: A Procedure to Evaluate Mosquito Larval Mortality following Direct Contact with Test Larvicidal Compound

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2025

In this video, we describe the larval contact assay to evaluate the toxicity of the dopamine receptor antagonist amitriptyline on the third instar stage larvae of mosquitoes, known vectors of several human infectious diseases. Assessing the larval mortality upon incubation with different amitriptyline concentrations over different time intervals helps determine its lethal concentration 50.

Close Relationships and Culture

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2025

Culture shapes how people approach attraction, choose partners, and build long-term relationships. While some preferences in mate selection appear consistent across cultures, such as men valuing physical attractiveness and women emphasizing financial resources, cultural contexts influence how these preferences are expressed and prioritized. Marriage extends beyond romantic ideals in many societies and is deeply embedded in social, economic, and religious frameworks.The Role of Culture in Mate...

Development of an In Vitro Ocular Platform to Test Contact Lenses

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Cited by 14 •

2016

Current in vitro models for evaluating contact lenses (CLs) and other eye-related applications are severely limited. The presented ocular platform simulates physiological tear flow, tear volume, air exposure and mechanical wear. This system is highly versatile and can be applied to various in vitro analyses with CLs.

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