Dynamic Time Warping

Dynamic Time Warping (DTW) is an algorithm for measuring similarity between sequences that may differ in speed, timing, or length, making it valuable for comparing signals that are not synchronized. It builds a distance matrix between samples and uses dynamic programming to find a minimum-cost warping path, subject to continuity and boundary constraints, that aligns corresponding features while allowing local expansion or compression of the time axis. In engineering, DTW supports speech and audio recognition, machinery-condition monitoring, sensor-data alignment, and gesture or motion analysis, helping systems detect recurring patterns despite variable operating rates and timing.

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Research

JoVE Journal - Medicine

Extended Time-lapse Intravital Imaging of Real-time Multicellular Dynamics in the Tumor Microenvironment

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Cited by 25 •

2016

This protocol describes the use of multiphoton microscopy to perform extended time-lapse imaging of multicellular interactions in real time, in vivo at single cell resolution.

High-Speed Time-Lapse Atomic Force Microscopy to Capture Nucleosome Dynamics

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2025

In this video, we demonstrate high-speed time-lapse atomic force microscopy, AFM, imaging techniques to study the dynamics of nucleosome complexes. As the AFM tip scans across the surface of the nucleosome, it detects alterations in the nucleosome height and records the DNA unwrapping over time.

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

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Cited by 10 •

2015

Closed-loop protocols are becoming increasingly widespread in modern day electrophysiology. We present a simple, versatile and inexpensive way to perform complex electrophysiological protocols in cortical pyramidal neurons in vitro, using a desktop computer and a digital acquisition board.

Real-time Imaging of Plant Cell Surface Dynamics with Variable-angle Epifluorescence Microscopy

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Cited by 10 •

2015

The goal of this protocol is to demonstrate how to monitor fluorescently-tagged protein dynamics on plant cell surfaces with variable-angle epifluorescence microscopy, showing blinking dots of GFP-tagged PATROL1, a membrane trafficking protein, in the cell cortex of the stomatal complex in Arabidopsis thaliana.

Recombination Dynamics in Thin-film Photovoltaic Materials via Time-resolved Microwave Conductivity

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Cited by 2 •

2017

A Time Resolved Microwave Conductivity technique for investigating direct and trap-mediated recombination dynamics and determining carrier mobilities of thin film semiconductors is presented here.

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