Micro Ct

Micro-CT, or micro-computed tomography, is a non-destructive imaging technique that creates three-dimensional representations of an object’s internal structure at micrometer-scale resolution. During scanning, the specimen rotates through an X-ray beam while detectors record changes in X-ray attenuation; computational reconstruction then converts these projections into a volumetric dataset of voxels. In engineering, Micro-CT reveals pores, cracks, inclusions, interfaces, and geometric defects without sectioning components. It supports quality control, failure analysis, materials characterization, and validation of manufacturing processes, including additive manufacturing. Quantitative measurements of internal architecture can guide design improvements and link processing conditions to mechanical performance.

Micro Ct - Related Videos

Education

JoVE Science Education - Engineering

Micro-CT Imaging of a Mouse Spinal Cord

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2023

Source: Peiman Shahbeigi-Roodposhti and Sina Shahbazmohamadi, Biomedical Engineering Department, University of Connecticut, Storrs, Connecticut It's a little-known fact that the discovery and (inadvertent) use of X-rays garnered the first ever Nobel Prize in Physics. The famous X-ray image of Dr. Röntgen's wife's hand from 1895 that sent shock waves through the scientific community looks like most modern day 2D medical X-ray images. Though it is not the newest technology, X-ray absorption...

Research

JoVE Journal - Bioengineering
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High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

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Cited by 13 •

2011

Non-destructive volume visualization can be achieved only by tomographic techniques, of which the most efficient is the x-ray micro computerized tomography ( CT).

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

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Cited by 37 •

2012

A method of functional imaging of mouse brown adipose tissue (BAT) is described in which cold-stimulated uptake of 18F-Fluorodeoxyglucose (FDG) in BAT is non-invasively assessed with a standardized micro-PET/CT protocol. This method is robust and sensitive to detect differences in BAT activities in mouse models.

Contrast-Enhanced Micro-CT Imaging of Cerebral Cavernous Malformation Lesions in a Mouse Brain

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2025

Source: Choi, J. P. et al. Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model. J. Vis. Exp. (2017)This video demonstrates the use of micro-CT imaging to visualize cerebral cavernous malformation (CCM) lesions in a mouse brain. It details the steps for sample preparation, imaging, and 3D image reconstruction to evaluate the density and location of CCM lesions in brain tissue.

Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT

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Cited by 15 •

2017

This study describes a protocol that uses 18F-FDG and positron emission tomography/computed tomography (PET/CT) imaging, together with kinetic modelling, to quantify the in vivo, real-time uptake of 18F-FDG into tissues.

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