Silicone Oil Grafting

Silicone oil grafting is an engineering method that covalently attaches silicone-based oil chains to a material, combining the substrate’s structural properties with silicone’s low surface energy, flexibility, and lubricity. The process typically uses reactive functional groups on the silicone oil and substrate to form stable chemical bonds, creating a grafted interfacial layer rather than a removable coating or physically trapped lubricant. This tailored surface can reduce friction, limit fouling, improve water repellency, and enhance compatibility between dissimilar materials. Applications include engineered coatings, elastomers, medical-device materials, seals, and microfluidic components, where durable control of surface behavior supports longer service life and improved performance.

Silicone Oil Grafting - Related Videos

Research

JoVE Journal - Engineering

Improved Polydimethylsiloxane (PDMS) Double Casting via Silicone Oil Treatment for Densely Packed Microstructure Replication

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2025

This protocol presents an improved demolding procedure for the Polydimethylsiloxane (PDMS) double casting technique by introducing silicone oil as a non-adhesive barrier between PDMS layers. Unlike plasma or chemical surface modification methods, this approach requires no specialized or costly equipment, making it a more accessible and cost-effective alternative.

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice

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Cited by 33 •

2019

Here, we present a protocol to induce ocular hypertension and glaucomatous neurodegeneration in mouse eyes by intracameral injection of silicone oil and the procedure for silicone oil removal from the anterior chamber to return elevated intraocular pressure to normal.

Enhanced Oil Recovery using a Combination of Biosurfactants

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Cited by 2 •

2022

We illustrate the methods involved in screening and identification of the biosurfactant producing microbes. Methods for chromatographic characterization and chemical identification of the biosurfactants, determining the industrial applicability of the biosurfactant in enhancing residual oil recovery are also presented.

Research

JoVE Journal - Engineering
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Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures

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2025

This protocol presents a light-induced method for fabricating slippery three-dimensional structures via sequential digital patterning and grafting on silane-coated nanoporous surfaces. This approach enables the spatially controlled formation of slippery regions, enabling patterned liquid repellency and the quantitative analysis of interfacial slipperiness, with applications in fluid manipulation and surface engineering.

Mouse Models for Graft Arteriosclerosis

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Cited by 17 •

2013

We describe protocols for our mouse graft arteriosclerois (GA) models which involve interposition of a mouse vessel segment into a recipient of the same inbred strain. By backcrossing additional genetic changes into the vessel donor, the model can assess the effect of specific genes on GA.

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